Words similar to duplex
Example sentences for: duplex
How can you use “duplex” in a sentence? Here are some example sentences to help you improve your vocabulary:
50 a month for a duplex on the Upper East Side that he didn't even live in.
Probe density may result in steric effects [ 17 ] and could affect the efficiency of duplex formation and kinetics of target capture [ 18 ] .
Pulmonary embolism was diagnosed on the basis of clinical symptoms and signs combined with a high probability ventilation-perfusion scan in 20 of the 30, a positive pulmonary angiogram in 6, a positive high resolution chest CT in 2 and an intermediate probability ventilation-perfusion scan combined with a high clinical suspicion in 2. The 8 proximal deep venous thrombosis was diagnosed by duplex ultrasonography in seven and contrast venography in 1. Thirty-one of the 38 patients were treated with intravenous heparin followed by oral warfarin, five by placement of an inferior vena caval and oral warfarin and two by placement of an inferior vena caval filter followed by intravenous heparin and oral warfarin
Earlier studies have shown that DAP, in DNA fragments, can widen the minor groove, as detected by reactivity towards uranyl nitrate or susceptibility to Dnase cleavage [ 29 ] , and can relieve compressions in the minor groove associated with A-tracts [ 30 ] . In contrast, NMR and molecular modeling studies of an oligonucleotide duplex containing MeC have demonstrated that, while this duplex still has a B-DNA conformation, there are differences in the structural parameters and thermal stability relative to the unmodified duplex [ 31 ] . An earlier study also found, in two closely related octanucleotide duplexes, that although the methylated duplexes retained their B-DNA conformation, different structural and thermal stability effects were seen [ 32 ] . Although these studies have been carried out with DNA-DNA and not DNA-RNA duplexes, it is possible that MeC substitution may have different structural consequences than DAP substitution.
Many studies have shown that a ribopurine rich strand bound to a deoxypyrimidine rich strand has a higher stability than the corresponding all deoxy strands which, in turn, have a higher stability than a deoxypurine rich strand bound to a ribopyrimidine rich strand [ 26 27 ] . These differences also suggest that further studies examining DAP or MeC incorporation into first strand cDNA, followed by formation of a DNA-DNA duplex, may not necessarily show the same effects as incorporation of these modified nucleotides into cRNA.
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