Example sentences for: ductal

How can you use “ductal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Female mice harboring the Wnt-1 transgene develop extensive mammary hyperplasia early in life, and 50% of them develop mammary ductal carcinomas by 6 months of age [ 27].

  • A recent study confirms this to be the case in breast cancer, where expression of TSP-1 in stroma adjacent to ductal carcinoma in situ is lost in cases with more aggressive histological features [ 30 ] . There are also reports, however, that fibroblast TSP-1 can induce matrix metalloproteinase-9 in breast tumor cells and gastric cancer tumor cells, and this in turn may lead to a more invasive phenotype [ 14 31 ] . In the present study, TSP-1 was not expressed differentially in the stroma of benign tissue specimens or malignant tissue specimens, nor in the epithelial component of breast tumors with or without metastases.

  • By 12 weeks of treatment, all three chemopreventive agents had a significant effect on glandular histology, with tamoxifen and 9cRA showing the greatest suppression of ductal development and lobule formation, and 4-HPR showing a relatively mild effect.

  • The four additional FFPE archived ductal carcinomas and the matched nodal metastases ( n = 8) were stained with the aforementioned antibodies using the antigen retrieval method now described to assess the utility of the antibodies on archived tissues.

  • Results showed that all three cases spanned a morphologic spectrum ranging from columnar cell hyperplasia to ductal carcinoma in situ . Case 1 (columnar cell hyperplasia) contained two ducts of interest lined by about 500 epithelial cells surrounded by morphologically distinct ME cell layers on the H&E-stained section (Fig.


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