Words similar to dsbh
Example sentences for: dsbh
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The classic AraC-like DSBH proteins appear to have a more universal distribution than the 2OG-Fe(II) dioxygenases, with diverse forms represented in archaea, bacteria and eukaryotes.
The closest relatives of the EGL-9 family are the proline hydroxylases with which they share a region of specific extended conservation amino terminal to the core DSBH domain (Figure 1).
The conserved portion of the 2OG-Fe(II) dioxygenase superfamily proteins comprises the core DSBH domain seen in the IPNS, DAOCS and CAS structures [ 8, 9, 10] and part of the amino-terminal α helix that showed considerable variability in both length and sequence between individual families (Figures 1, 2).
The DSBH region includes seven conserved strands that are common to all these proteins and are arranged in two sheets in a jelly-roll topology (Figures 2, 3).
This reflects the relative resilience of the core DSBH to insertions, and accounts for difficulties in unification of this superfamilyby sequence-based methods.
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