Example sentences for: drug-resistance

How can you use “drug-resistance” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A recent report describes an expression profiling approach as applied to bone marrow samples before and after treatment with the tyrosine kinase inhibitor STI-571 in patients with acute lymphoblastic leukemia [ 26 ] . This work clearly demonstrates utility of the approach in investigation of drug-resistance development in hematological malignancies.

  • Given the paradigm established with imatinib, other drug-resistance mutations in EGFR, either within or outside the tyrosine kinase domain, are likely to exist.

  • Further, we observed durable resuppression of plasma viral RNA level in many patients who had drug-resistance mutations off therapy that would otherwise be expected to affect part of their treatment regimen when reinitiated (see Table S1).

  • However, the authors emphasize that differences in the types and patterns of drug-resistance mutations are likely to differ between the subtypes, and that larger numbers of samples and further analyses are needed to exclude the possibility of new and/or rare subtype-specific mutations.

  • What they found was that all of the 55 drug-resistance mutations that have been known to occur in subtype B also occurred in at least one non-subtype-B isolate, and most of these mutations were also statistically associated with antiretroviral treatment in at least one non-B subtype.


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