Words similar to drug-resistance
Example sentences for: drug-resistance
How can you use “drug-resistance” in a sentence? Here are some example sentences to help you improve your vocabulary:
A recent report describes an expression profiling approach as applied to bone marrow samples before and after treatment with the tyrosine kinase inhibitor STI-571 in patients with acute lymphoblastic leukemia [ 26 ] . This work clearly demonstrates utility of the approach in investigation of drug-resistance development in hematological malignancies.
Given the paradigm established with imatinib, other drug-resistance mutations in EGFR, either within or outside the tyrosine kinase domain, are likely to exist.
Further, we observed durable resuppression of plasma viral RNA level in many patients who had drug-resistance mutations off therapy that would otherwise be expected to affect part of their treatment regimen when reinitiated (see Table S1).
However, the authors emphasize that differences in the types and patterns of drug-resistance mutations are likely to differ between the subtypes, and that larger numbers of samples and further analyses are needed to exclude the possibility of new and/or rare subtype-specific mutations.
What they found was that all of the 55 drug-resistance mutations that have been known to occur in subtype B also occurred in at least one non-subtype-B isolate, and most of these mutations were also statistically associated with antiretroviral treatment in at least one non-B subtype.