Words similar to drotrecogin
Example sentences for: drotrecogin
How can you use “drotrecogin” in a sentence? Here are some example sentences to help you improve your vocabulary:
In all patients receiving drotrecogin alfa (activated) in clinical trials, serious bleeding events associated with invasive procedures accounted for 39.
These recommendations are based on the observation that the concentration of drotrecogin alfa (activated) in plasma is below the assay level of detection in a large majority of patients within 2 hours of discontinuing the infusion [ 11 ] .
7% associated with drotrecogin alfa (activated) use reported in the pivotal, phase 3 trial F1K-MC-EVAD (PROWESS) [ 4 ] . These mortality rates are lower than recent mortality rate estimates for severe sepsis, which ranged between 30% and 50% [ 7 ] and lower than the combined placebo rate from controlled clinical trials of 31.
Neither APACHE II score (< 25 or ≥ 25) nor concomitant heparin use appear to alter serious bleeding event rates associated with drotrecogin alfa (activated) substantially.
The consistency of treatment effects in drotrecogin alfa (activated) patients might have been expected given that, for the most part, inclusion and exclusion criteria were similar across trials.