Words similar to drastic

Example sentences for: drastic

How can you use “drastic” in a sentence? Here are some example sentences to help you improve your vocabulary:

Concomitant with this development of asymmetrical structure, the AAA1 protomer of the dynein motor unit evolved a functional dominance, in which it alone retains the full ability for binding and hydrolysis of ATP, while AAA2, AAA3 and AAA4 have lost the capability for hydrolysis and the most degenerate protomers AAA5 and AAA6 show no significant binding of ATP [ 20 21 22 ] . In midasin, the specialization of AAA protomers appears to have taken a less drastic course than in dynein.
Loss of PfPP1 resulted in concomitant inhibition of parasite growth as evidenced by the drastic reduction in 3H-hypoxanthine incorporation.
None of the enzymes displayed a significant reduction in K m [dNTP] when the heteropolymeric DNA\DNA template primer was used, although the p66 INS/p66 INSand p66 INS/p51 INSmutants exhibited drastic reduction in catalytic efficiency.
As the funding agency, LSNY subcontracted with the local boards to provide legal services, and was left with only the "drastic remedy" of defunding a local program if problems in management or delivery of services were uncovered, he said.
This, together with the phyletic distributution of the AraC and 2OG-Fe(II) dioxygenase superfamilies, leads us to speculate that the 2OG-Fe(II) dioxygenase superfamily evolved from the AraC-like superfamily in bacteria through drastic sequence divergence that eliminated significant sequence similarity, followed by fixation of the modified active-site configuration.