Words similar to doxorubicin
Example sentences for: doxorubicin
How can you use “doxorubicin” in a sentence? Here are some example sentences to help you improve your vocabulary:
that antioxidant enzyme activity in the liver was altered following long term consumption of n-3 PUFAs [ 14 ] . We reasoned that alteration of antioxidant enzyme activity in the tumor by consumption of n-3 PUFAs prior to chemotherapy treatment could increase oxidative stress within the tumor, perhaps resulting an enhanced sensitivity to oxidative stress induced by doxorubicin (DOX).
There are, however, certain aromatic polyketides, including the anticancer drug doxorubicin, an antiparasitic agent called frenolicin, and the estrogen receptor agonist R1128, that have different starters.
The results of cell culture and animal studies have shown that omega 3 polyunsaturated fatty acids (n-3 PUFAs) selectively killed cancer cells in vitro [ 1 ] . Furthermore, n-3 PUFAs incorporated into animal diets have reduced tumor growth rates in vivo [ 2 3 4 ] . The prevailing hypothesis for the reduction in tumor cell growth, in vitro or in vivo , by supplementing the diet with high levels of n-3 PUFAs has been that the incorporation of n-3 PUFAs into cell membranes of the tumor cells increased the susceptibility of the cells for lipid peroxidation and that the products of lipid peroxidation subsequently accumulated to cytostatic or cytotoxic levels [ 2 5 6 7 ] . It has also been reported that supplementing the diet of cancer xenograft bearing mice with n-3 PUFAs could increase the efficacy of edelfosine [ 8 ] , doxorubicin [ 9 ] , mitomycin [ 10 ] , cyclophosphomide and 5-fluorouracil [ 11 ] or irinotecan [ 12 ] against the tumor.
Results of the scoring of the numbers of peripheral erythrocytes with and without a micronucleus are summarized in Table 5. Included in Table 5are data from mice treated with a series of injections of doxorubicin.
ANC = absolute neutrophil count; CAF = chemotherapy with cyclophosphamide, doxorubicin, fluorouracil; MDACC = MD Anderson Cancer Center.
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