Words similar to downstream
Example sentences for: downstream
How can you use “downstream” in a sentence? Here are some example sentences to help you improve your vocabulary:
Despite numerous reported differences, it does appear that diverse GPCRs share common mechanistic themes during ERK stimulation, including the tyrosine-phosphorylation of Shc and its complexing with Grb2, mSOS recruitment, the GTP-loading of Ras, and Raf-1 activation leading to MEK-1 phosphorylation [ 1 ] . However, the progression of each of these downstream events after GPCR stimulation depends first on the tyrosine phosphorylation of a membrane-bound protein that will be used as a scaffold, which will bind the other proteins (e.g.
A set of nested antisense primers that is 300 bps further downstream also gave negative results.
NarL-phosphate then negatively regulates dmsABC operon expression [ 4 ] . Additional regulators of dmsABC expression have also been described that involve molybdenum dependent gene expression via the ModE transcription factor, and integration host factor (IHF) that interacts with DNA at a downstream site called P2 [ 4 6 11 12 ] . Neither the presence of TMAO nor DMSO, substrates for the DMSO reductase, further modulate dmsABC gene expression [ 4 6 ] .
Strong conservation of the sequences upstream and downstream from the repeats allowed the design of very specific primers that generate extremely reproducible results.
The UCSF group initially handed over further development of a drug candidate to the Institute for OneWorld Health (iOWH), one of the nonprofit organizations that has sprung up to meet “downstream” drug development needs for neglected diseases (see Sidebar).
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