Words similar to doublet
Example sentences for: doublet
How can you use “doublet” in a sentence? Here are some example sentences to help you improve your vocabulary:
A doublet of monomers has been previously observed for VR1 expressed in CHO cells [ 23 ] . In that case, treatment of cells with peptide- N -glycosidase F eliminated the larger monomer band, suggesting that it represented a glycosylated form of VR1.
This suggests that the 55/57-kDa human myocilin doublet is due to differential glycosylation and that the site of N-linked glycosylation on human myocilin is Asn 57.
Human myocilin has been shown to migrate as a 55/57-kDa doublet by SDS-PAGE/immunoblot analysis [ 10 11 12 16 17 ] . The modification accounting for this molecular weight difference is hypothesized to be due to differential glycosylation.
The lack of glycosylation seen in the in vitro canine pancreatic microsomal membrane translation experiment may again be due to poor 55/57-kDa myocilin doublet resolution or the inability of this artificial system to faithfully glycosylate myocilin.
Although the difference in apparent size in that study was 19 kDa and we see a difference of only 4 kDa (Figure 2C), we wondered whether glycosylation might explain our doublet as well.