Words similar to dose-related
Example sentences for: dose-related
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In contrast, an inverse dose-related effect was observed between adeno-RGS3 and GnRH-stimulated LH secretion (Fig.
dizziness, headache and insomnia) are a more frequent occurrence, occurring in up to 25% of those receiving chemoprophylactic doses and 90% of patients receiving therapeutic doses [ 1 ] . Higher blood levels of mefloquine are reached under prophylactic as compared to therapeutic regimens [ 1 2 ] . The relative incidence of adverse effects is, therefore, probably dose-related, although the concomitant effect of malaria during treatment cannot be dismissed.
The effect was dose-related, with an ED 50 of 66 μM (95% confidence interval, 33 - 130 μM).
utilis) that produce a dose-related increase in the clotting time of blood induced by carpet viper venom ( Echis carinatus ) would be useful against bites from Bothrops species that cause haemorrhage at the point of injection due to the inhibition of the clotting mechanism [ 40 ] . Antivenom compounds so far isolated from plants include protocatechuic acid, a catechin-gallo-catechin tannin, caffeic acid derivatives (chlorogenic acid, cynarin), coumarins (bergapten), flavonoids (rutin, isoscutellarein, kaempferol, quercetin, hesperidin), ar-turmerone, alkaloids (aristolochic acid), triterpenoids, triterpenes, coumestans (wedelolactone), sterols (sitosterol, stigmasterol, beta-amyrin), triterpenoid glycosides, alkaloids (allantoin) and lignoflavonoids [ 43 40 44 42 ] . Many relevant compounds are widely distributed nitrogen-free, low molecular weight compounds (except aristolochic acid, an untypical non-basic, nitro-derivative) [ 38 ] . The structural similarities of certain plant chemicals found in plants used for snakebites are an isoflavone skeleton, acidic nature and dioxygenated functionality [ 44 ] .
8 μM) [ 3 4 ] . The relative incidence of adverse effects is, therefore, probably dose-related, although the concomitant effect of malaria during treatment cannot be dismissed.
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