Words similar to dose-dependent
Example sentences for: dose-dependent
How can you use “dose-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:
Total and HDL cholesterol, triglycerides, alcohol usage, and systolic blood pressure all showed a dose-dependent association with smoking intensity ( p <0.
To examine whether the p44/42 MAPK pathway mediates insulin signaling in the H441 cells, PD98059, an inhibitor of the p44/42 MAPK pathway, was used [ 9 ] . PD98059 binds to the dephosphorylated form of MEK and prevents its activation in vivo with an IC 50 of 10 μM [ 9 ] . PD98059, added alone, significantly decreased SP-A mRNA levels in a dose-dependent manner (Fig.
Due to the increased molecular weight of the EGFP-tagged cPLA 2 , the two forms of cPLA 2 did not separate as well, making the gel shift more difficult to visualize, but generally mirrored the gel shift characteristics of the endogenous cPLA 2 . These results suggest that, in response to MEK1 inhibition, there is a quantitative, dose-dependent decrease in AA release that correlates well with the loss of ERK activation, but not with the extent of cPLA 2 Ser 505phosphorylation.
Results indicated that 15d-PGJ 2 prevented H 2 O 2 induced cytotoxicity in primary human RPE cultures in a dose-dependent manner (Fig.
In animals, PEEP decreases hepatosplanchnic perfusion in a dose-dependent manner, with a limited effect at PEEP levels of less than 10 cmH 2 O [ 2 4 5 ] . Alterations in splanchnic blood flow attributed to PEEP occur in parallel to those in cardiac output and consequently can be reversed with restoration of blood pressure [ 4 13 ] . Despite experimental evidence, concerns regarding the effects of PEEP on splanchnic perfusion remain theoretical because large studies in humans are lacking.
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