Words similar to domoic
Example sentences for: domoic
How can you use “domoic” in a sentence? Here are some example sentences to help you improve your vocabulary:
4 mM) [ 39 ] , rapid and complete dissolution of domoic acid was only consistently observed in our laboratory when preparing a stock domoic acid solution of 12.
The results of this study demonstrated that even though the highest concentration of domoic acid tested, namely 1 mM, did not affect rat neonatal microglia viability in vitro, domoic acid concentrations as low as 10 μM were clearly cytotoxic to cerebellar granule neurons after a 6 hour exposure.
Our electrospray mass spectrometry results clearly showed that undegraded domoic acid was present, demonstrating the stability of domoic acid in the aqueous solutions that had been frozen at -80°C and thawed prior to use in the experiments.
Furthermore our observations suggest that in vivo, brain microglia as well as the mediators released by this cell type in brain tissue, would appear to play a limited role in the rapid and potent domoic acid neurotoxicity observed in neonatal rats after a short-term administration of domoic acid.
.. ", together with paralytic, neurotoxic, diarrhetic and ciguatera fish poisoning (FDA website: http://vm.cfsan.fda.gov/~dms/haccp-2f.html) [ 14 ] . Recent behavioral toxicity studies in rodents, have confirmed that domoic acid is a very rapid and potent neurotoxin in newborn rats, at doses far lower than in adult animals [ 15 16 17 ] . Even though hippocampal pyramidal neurons and mossy fiber terminals appear to be selectively targeted in vivo by domoic acid in rat [ 18 ] and cynomolgus monkey brain [ 19 ] , recently domoic acid was shown to affect glutamate uptake by astrocytes in vitro and " ...thus produced neurotoxicity.
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