Example sentences for: dlg

How can you use “dlg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We then performed PCR using primers anchored in the introns of DLG5 for each of the exons on both the normal haploid DNA and the disease bearing haploid DNA.

  • It is notable that the PDZ domains predicted for the DLG5 protein do not have the GLGF motif [ 2 ] , present in most members of the MAGUK family.

  • The DLG5 gene encodes for a protein that is a member of the MAGUK (Membrane Associated Guan late Kinase homologs) family of proteins located in the plasma membrane [ 2 ] . MAGUK is a new family of proteins that act as a molecular scaffold for intracellular signaling pathways [ 11 ] . The MAGUK family of proteins is characterized by domains that interact with other proteins to create an assembly of large multi-protein complexes [ 10 ] . The PDZ (PSD-95, DLG and ZO-1) domains are the best characterized for their binding to the C-terminal region of channels and transmembrane proteins [ 11 ] . Usually each protein has 1-3 copies of such domains [ 8 12 13 ] . The SH3 domain (Src homology 3) are present in proteins that couple transmembrane receptors to signaling molecules [ 14 ] . The presence of this domain in MAGUKs increases their possibilities of interacting with signaling pathways.

  • Cloning and sequencing of the DLG5 cDNA

  • Thus, DLG50 is excluded as a possible cause of familial atrial fibrillation in these families.


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