Words similar to dispensable
Example sentences for: dispensable
How can you use “dispensable” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, they are dispensable for DNA damage-dependent activation of the Rad26/Rad3-kinase complex [ 18 ] , but are required for the Rad3-dependent phosphorylation of Chk1 [ 23 ] . Structural predictions of Hus1, Rad1 and Rad9 have led to the proposal that all three fold similarly to the subunits of Proliferating Cell Nuclear Antigen (PCNA) [ 24 25 26 ] . Consistent with these predictions, PCNA exists as a homotrimer [ 27 ] while Hus1, Rad1 and Rad9 all interact and possibly form a heterotrimer [ 25 28 ] . In addition, Rad17 has sequence similarity and physical interactions with subunits of Replication Factor C (RFC) [ 29 30 ] . Based on the RFC-PCNA paradigm, the Rad17-RFC complex may load the PCNA-like Rad9-Rad1-Hus1 (9-1-1) complex onto genomic lesions discovered by the Rad26/Rad3 complex.
Thus, hydroxylamine and D,L-alpha-amino-caprylic acid were the most easily dispensable (2/21 for each), followed closely by D-amino-N-valeric acid (3/21) and 2-amino-N-valeric acid (5/21).
2) There may be a hierarchy from "most-dispensable-to-least dispensable" substrate utilization for both carbon and nitrogen molecules.
At this point, however, it is not clear what the exact structural requirements for retrohoming are, or which tertiary interactions are dispensable for the reaction.
It is dispensable for chromosome pairing and synapsis in some organisms, but is required in others [ 22 24 25 26 27 28 ] . Budding yeast spo11Δ (null) mutants lack chromosome pairing, but catalytic site tyrosine mutants ( spo11-Y135F ) support significant levels of DSB-independent pairing [ 29 ] , so the function of Spo11 proteins in pairing may be separable from its function in catalyzing recombination.
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