Example sentences for: disequilibrium

How can you use “disequilibrium” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ADPRT = adenosine diphosphate ribosyltransferase; cM = centiMorgan; C-TDT = combined S-TDT and TDT; ESRRG = estrogen-related receptor gamma; HLA = human leukocyte antigen; kb = kilobasepairs; LOD = logarithm of odds ratio; MIM = Mendelian Inheritance in Man (database; see [ 1]); PARP = poly ADP ribosyl polymerase; PCR = polymerase chain reaction; PDT = pedigree disequilibrium test; SLE = systemic lupus erythematosus; S-TDT = discordant-sib TDT; TDT = transmission disequilibrium test; T:NT = ratio of transmitted to nontransmitted alleles.

  • Despite having much higher mutation rates than diallelic polymorphisms, there is abundant evidence that highly informative STRPs of the type found within Screening Sets are generally powerful markers for detection of linkage disequilibrium [eg [ 31 32 ] ]. It is unclear, however, whether dinucleotide or tetranucleotide STRPs are superior in this regard.

  • Chi-square analyses of observed and expected frequencies of each genotypic class showed no linkage disequilibrium between the exon III 7-repeat and the -521 site or the 120 bp repeat polymorphism.

  • The pedigree disequilibrium test (PDT) improves upon these two tests by generating a measure of linkage disequilibrium for every discordant sibship and triad in a pedigree [ 17].

  • Although it was hypothesized that the polymorphism (A2 allele) could result in an additional Sp1 binding site with enhanced promoter activity and an increased rate of transcription [ 1 ] , this was not found in experimental studies [ 20 21 ] . Nonetheless, two studies found that both premenopausal and post-menopausal women with the variant A2 allele had higher levels of circulating estrogens than those with common alleles, indicating that the polymorphism may be in linkage disequilibrium with another functional polymorphism or that it may affect hormone levels through some other mechanism [ 4 22 ] .


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