Words similar to discontinuation
Example sentences for: discontinuation
How can you use “discontinuation” in a sentence? Here are some example sentences to help you improve your vocabulary:
The prazosin arm had the highest rate of adverse effects, leading to discontinuation of treatment.
However, in this patient's case with her prominent features of a hypersensitivity reaction and failure to improve after SSZ discontinuation, corticosteroids were administered to hasten recovery.
In addition, a possible opportunistic fungal, mycobacterial, or other atypical infection was raised with the high fevers, low grade DIC, and disseminated granulomas that persisted after SSZ discontinuation.
Study discontinuation in the repeated interruptions arm was due to protocol violation ( n = 1; patient restarted therapy during interruption out of protocol), loss to follow-up ( n = 1; patient imprisoned), and virological failure during on-therapy period ( n = 1; further discussed below).
Sulfasalazine (SSZ) is a widely used and highly effective anti-inflammatory agent in the treatment of Crohn's disease and ulcerative colitis [ 1 2 3 ] . SSZ is also being used with increasing frequency in the treatment of various rheumatolgical disorders [ 4 5 6 7 ] . SSZ is preferred over other agents such as gold and penicillamine in rheumatology patients due to its more favorable side effect profile [ 8 9 10 ] . Nonetheless, rash, fever, and dyspepsia occur in 3% to 20% of treated patients [ 7 11 12 ] . These reactions are usually dose dependent and improve with dose reduction or discontinuation [ 7 12 ] . However, more serious but less common side effects have also been reported [ 13 14 15 16 17 18 19 ] . We now report a severe systemic reaction to SSZ in a 21-year-old female with rheumatoid arthritis characterized by granulomatous infiltration of the bone marrow, colon and small bowel as well as cholestatic hepatitis and seizures.
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