Words similar to discernable
Example sentences for: discernable
How can you use “discernable” in a sentence? Here are some example sentences to help you improve your vocabulary:
Histologies included 13 squamous cell, 12 adenocarcinoma, one adeno/squamous cell, and 12 unspecified NSCLC (undifferentiated or poorly differentiated non-small cell carcinoma) because specific cell type was not discernable from available biopsies.
In comparison to the two general alternative mechanisms utilized by known transforming viruses to promote cell-cycle progression, namely, by activating or bypassing endogenous D-type cyclins (herein, referred to as "cyclin D"), it has not been established whether HIV-1 gene products trigger either cyclin D-dependent or cyclin D-independent proliferation in non-lymphoid tissues [ 15 ] . In infected renal epithelium, HIV-1 could disrupt the inhibitory binding of pRb to E2F independent of endogenous cyclin D, analogous to transforming viral mechanisms that bypass and down-regulate endogenous cyclin D, such as SV-40 T antigen binding to pRb [ 16 ] , HHV-8 v -cyclin binding to and activating cyclin-dependent kinase-6 (CDK) [ 17 ] , and activation of cyclin E by EBV-induced c -myc [ 18 ] . Alternatively, HIV-1 could activate cyclin D-dependent proliferation, as exemplified by RSV v -src-mediated signaling [ 19 ] . In most tissues, the selective activation of these cell-cycle pathways is readily discernable.
Disease-causing myocilin mutants are less soluble in Triton [ 16 ] and are retained by the cell [ 12 ] . Other studies have shown that a truncated form of myocilin does not get secreted [ 20 21 ] and that mouse MYOC knockouts are without discernable phenotype [ 42 ] . Furthermore, a human hemizygous individual containing an interstitial deletion of chromosome 1, which encodes MYOC , was without evidence of glaucoma [ 43 ] and another patient homozygous for a severly truncated form of myocilin had no evidence of glaucoma [ 44 ] or other discernable phenotypes.
These changes included posterior subcapsular nucleic acid staining, absence of posterior sutures, and small irregularly shaped cells, not arranged in any discernable pattern, in the equatorial/bow region.
Under this definition, in practice, there has been no discernable USO cost.
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