Words similar to directional
Example sentences for: directional
How can you use “directional” in a sentence? Here are some example sentences to help you improve your vocabulary:
The correlation between average mutational effects (α) and directional epistasis (β) described by Wilke and Adami [ 11 ] implies that whether a reference sequence shows synergistic or antagonistic epistasis depends on whether it lies near the center of a dense cluster of high-fitness sequences in genetic space, or on the fringes of such a cluster.
This is in agreement with the reported literature where it has been reported that IL-12 can act only on pre-stimulated cells and has little or no effect on resting lymphocytes [ 27 ] . IL-12 is a cytokine produced to some degree by B lymphocytes but mostly by phagocytic cells including monocytes, macrophages, neutrophils, epidermal cells, keratinocytes and dendritic cells which are among the first cells to encounter a foreign antigen during infection in response to bacteria, bacterial products, intracellular parasites, etc [ 2 ] . It was found that IL-12 induced directional migration of highly enriched preparations of NK cells and CD3 activated cells but not resting T cells and monocytes.
This correlation is fully consistent with the hypothesis that directional epistasis depends on the location of the reference sequence relative to other high-fitness genotypes.
The first physical step in directional motility is the extension of cellular processes termed pseudopods [ 11 ] . Pseudopodia are flattened, fan shape cellular protrusions enriched in signaling molecules and cytoskeletal elements including filamentous actin, which is preferentially nucleated at the leading edge of a migrating cell [ 12 ] . A key candidate for regulation of the T lymphocyte actin cytoskeleton is the GTP-binding protein Rho.
Of the 6,525 human and 566 mouse EST libraries considered, 899 and 176, respectively, had an LQS of greater than 0.95, indicating that these libraries were generated by an efficient method of directional cloning.
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