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Example sentences for: direct
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GAL1 promoter in a centromeric or episomal plasmid, respectively, indirect immunofluorescence of HA-Ppt1p or direct fluorescence from EGFP-Ppt1p showed that both proteins were also localized throughout the cell.
This is due to the direct toxic effects of the contrast material on nerve cells [ 10], which result from its osmotic effect after intracellular penetration.
The most sophisticated published treatments for determination of significance use Bayesian probability methods, maximum likelihood procedures, or multiparameter fitting to analyze samples of gene expression data [ 4 5 6 ] . As pointed out by others, the lack of replicates of individual sequence intensities blocks the most direct route to estimates of variance.
In addition to providing a direct measure of PA and FPM, PKQuest also provides, for the first time, quantitative information about the rate of intestinal absorption of an orally administered drug that has non-linear metabolism.
Females lack an estrous cycle and anestrous adults are dependent upon direct contact with a non-volatile male pheromone for induction of estrus [ 8 ] . Hormonal control of scentmarking and sexual behavior of this species (hereinafter, opossum) has been described in some detail [ 9 10 ] . Estrus is induced when females nuzzle scentmarks from the androgen-dependent suprasternal (chest) gland [ 10 11 ] . Nuzzling delivers nonvolatile chemical signals to the vomeronasal organ (VNO) [ 12 ] and surgical removal of the VNO prevents induction of estrus by scentmarks alone [ 13 ] , although cautery ablation of the VNO fails to prevent ovarian activation and ovulation in females that are caged with adult males [ 14 ] . While anestrous adults are reliant on male pheromone for reproductive activation, spontaneous postlactational estrus occurs in the absence of direct contact with male pheromone [ 15 ] .
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