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Example sentences for: diamide

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In terms of the genes induced in the UPR (identified as the top 30 genes or so in cluster 58), the effects of diamide were most similar to those triggered by the reducing agent DTT (Figure 8d).
In contrast, when the microarray clustering was performed on the basis of genes involved in oxidative stress defense, (the top 24 genes belonging to cluster 4), diamide was most similar to hydrogen peroxide and menadione, which inflict oxidative damage by generating reactive oxygen species (Figure 8c).
In contrast to this relationship, when the experiment clustering was performed on genes encoding ER-resident proteins, the effects of zinc starvation were most similar to those inflicted by DTT and diamide (Figure 8d), suggesting that zinc limitation may initiate the UPR.
That the effects of diamide were similar to those of different environmental conditions depending on the genes analyzed reflects the diverse effects of this drug on the cell (Figure 8f).
In addition, KAR2 also has significant membership in a second cluster (cluster 11 in Figure 5d), which is composed of genes that were induced following heat shock and diamide treatment.