Words similar to diamide

Example sentences for: diamide

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An example is the sulfhydryl-oxidizing drug diamide, which affects many aspects of cell biochemistry.
That the effects of diamide were similar to those of different environmental conditions depending on the genes analyzed reflects the diverse effects of this drug on the cell (Figure 8f).
By crosslinking protein sulfhydryl groups, diamide is thought to disrupt protein structure and trigger oxidative stress [ 57, 58], both of which are likely to perturb normal ER functions [ 59].
Roughly 40% (14/36) of the top characterized genes associated with this group encode protein-folding chaperones localized to different subcellular regions (including those that encode the cytosolic Hsp90 and Hsp70 factors, the mitochondrial Hsp10/Hsp60p and Ssc1p, and the ER- and mitochondrial-associated Ssa1p), and their induction following heat shock and diamide treatment is likely to be in response to widespread protein unfolding inflicted by these conditions.
In contrast, when the microarray clustering was performed on the basis of genes involved in oxidative stress defense, (the top 24 genes belonging to cluster 4), diamide was most similar to hydrogen peroxide and menadione, which inflict oxidative damage by generating reactive oxygen species (Figure 8c).