Example sentences for: diamide

How can you use “diamide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition, KAR2 also has significant membership in a second cluster (cluster 11 in Figure 5d), which is composed of genes that were induced following heat shock and diamide treatment.

  • An example is the sulfhydryl-oxidizing drug diamide, which affects many aspects of cell biochemistry.

  • In contrast to this relationship, when the experiment clustering was performed on genes encoding ER-resident proteins, the effects of zinc starvation were most similar to those inflicted by DTT and diamide (Figure 8d), suggesting that zinc limitation may initiate the UPR.

  • Roughly 40% (14/36) of the top characterized genes associated with this group encode protein-folding chaperones localized to different subcellular regions (including those that encode the cytosolic Hsp90 and Hsp70 factors, the mitochondrial Hsp10/Hsp60p and Ssc1p, and the ER- and mitochondrial-associated Ssa1p), and their induction following heat shock and diamide treatment is likely to be in response to widespread protein unfolding inflicted by these conditions.

  • By crosslinking protein sulfhydryl groups, diamide is thought to disrupt protein structure and trigger oxidative stress [ 57, 58], both of which are likely to perturb normal ER functions [ 59].


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