Example sentences for: dfz
How can you use “dfz” in a sentence? Here are some example sentences to help you improve your vocabulary:
If the carboxyterminus of LRP6 can interact with Axin independently of DFz2 and Dsh, it might reduce the cytoplasmic level of Axin and help stabilize β-catenin.
DFz2, like other members of the Fz protein family, contains a cysteine-rich domain (CRD) near the aminoterminus, followed by a seven-transmembrane (7-TM) domain and a cytoplasmic carboxyterminal tail.
Importantly, the synergistic effect of co-transfected Wg and DFz2 plasmids, approximately 1000-fold, was also dramatically reduced by addition of inhibitory RNA against Arr (Figure 2B), implying that endogenous Arr is required for the stimulatory effect of exogenous DFz2 on Wg signaling.
Thus S2 cells express mRNAs for Arr, DFz2 and DFz3, but mRNAs for DFz1 and DFz4 are either absent or below levels required for detection with our RT-PCR assay.
This result also suggests that DFz2 and Arr work cooperatively to transduce a Wg signal.