Example sentences for: dfz

How can you use “dfz” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • LRP6 and an aminoterminal mutant of LRP6 can stimulate the Wg signaling pathway, but the ability of LRP6 to replace the requirement for Arrow in the synergy between Wg and DFz2 requires the aminoterminus of LRP6

  • As additional controls in these experiments, we showed that inhibitory RNA against Dsh, a cytoplasmic phosphoprotein believed to mediate Wg signaling via Fz receptors, blocks about 60% of signaling produced by co-transfection with Wg and DFz2 plasmids.

  • In addition, the synergistic effect of Wg and DFz2ΔC was blocked by Dsh dsRNAi (data not shown), implying that Dsh is required to transduce the signal from Wg through DFz2ΔC to β-catenin.

  • To ask whether LRP6 can replace the requirement for endogenous Arr in the synergy between Wg and DFz2, as observed earlier in Figure 2B, we again used Arr-specific dsRNAi to try to block the strong activation of signaling by Wg plus DFz2, in the presence and absence of the LRP6 constructs (Figure 5C).

  • Therefore, the interaction between DFz2 and Dsh does not depend solely on the carboxyterminus of DFz2.


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