Example sentences for: dff

How can you use “dff” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As with DFF45, PARP cleavage was significantly enhanced in BRCA1+ cells suggesting that decreased DNA repair capacity in BRCA1+ cells may, in part, be due to premature inactivation of PARP.

  • Degradation of full length DFF45 was used to indicate caspase 3 activity.

  • In contrast, in BRCA1+ cells, full length DFF45 was only 71% of control at 0.5 h, 16% of control at 1 h, and 10% of control at 1.5 h (Table 1).

  • Instead, this amino-terminal mutation favored elevated caspase 3 levels that subsequently facilitated enhanced apoptosis by inactivating the caspase-dependent DNA repair proteins PARP and by inactivating DFF45, an inhibitor of the caspase-dependent DNase, DFF40.

  • Disruption of this domain triggered an elevated caspase 3-dependent apoptotic response and affected downstream proteins such as DFF45 and PARP.


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