Words similar to dff

Example sentences for: dff

How can you use “dff” in a sentence? Here are some example sentences to help you improve your vocabulary:

This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.
Degradation of full length DFF45 was used to indicate caspase 3 activity.
In both cell lines, DFF45 began to significantly degrade by 1 h after treatment.
As with DFF45, PARP cleavage was significantly enhanced in BRCA1+ cells suggesting that decreased DNA repair capacity in BRCA1+ cells may, in part, be due to premature inactivation of PARP.
Disruption of this domain triggered an elevated caspase 3-dependent apoptotic response and affected downstream proteins such as DFF45 and PARP.