Example sentences for: detergent-insoluble

How can you use “detergent-insoluble” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Indeed, we report here that the palmitoylated cysteine-string is responsible for the targeting of Rlk to RAFTs: detergent-insoluble, glycolipid-enriched membrane microdomains that contain many signaling molecules, including Src family kinases.

  • For example, crosslinking of the T-cell receptor results in a transition of the receptor complex to a detergent-insoluble fraction [ 43, 44, 45], as well as to increased turnover of TCR components [ 46].

  • This phenomenon could result from either a change in protein location to a detergent-insoluble fraction or increased turnover of Rlk.

  • Data suggest that, for Itk, this membrane association specifically targets the protein to glycolipid enriched detergent-insoluble membrane microdomains known as "RAFTs" and that both this association and the activation of Itk requires the PH domain [ 29].

  • In particular, since Rlk can be associated with detergent-insoluble RAFTs, it is possible that a change in subcellular localization or associations may contribute to the decrease in Rlk protein.


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