Words similar to desferrioxamine
Example sentences for: desferrioxamine
How can you use “desferrioxamine” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the first study, 144 patients with thalassemia major and relatively low serum ferritin concentrations (1,500 - 3,000 ng/mL) were randomized to either deferiprone (n = 71) or desferrioxamine (n = 73) and followed for one year [ 28 ] . Although, the primary efficacy measure was the reduction of serum ferritin, HIC was assessed in a small subgroup of patients willing to undergo repeat liver biopsy: 21 in the deferiprone and 15 in the desferrioxamine group.
To many, deferiprone may not appear as a first-line chelator but rather as an alternative to desferrioxamine should the latter not be usable.
Several systematic, qualitative reviews [ 2 8 23 24 ] highlight the clinical benefits of desferrioxamine treatment and, with respect to iron loading, acknowledge its ability to maintain harmless hepatic iron levels in properly chelated patients.
The doses of deferiprone - even in the optimal dose group - are relatively low, compared to the desferrioxamine doses, which in most studies are well above the recommended 40 mg/kg/day.
3 mg/g) deferiprone (overall p < 0.0001; p = 0.06 and p = 0.0002 for pairwise comparisons of desferrioxamine vs optimal and low dose deferiprone, respectively).
Loading...