Words similar to desferrioxamine
Example sentences for: desferrioxamine
How can you use “desferrioxamine” in a sentence? Here are some example sentences to help you improve your vocabulary:
Despite the fact that compliance is improved on deferiprone, this highlights the dangers of assuming that this drug, with potential toxicity greater than that of desferrioxamine, should be implemented in patients struggling with desferrioxamine, as proposed by some clinicians.
The doses of deferiprone - even in the optimal dose group - are relatively low, compared to the desferrioxamine doses, which in most studies are well above the recommended 40 mg/kg/day.
The studies identified were carefully evaluated for eligibility; they were included if they (i) enrolled subjects with thalassemia major - irrespective of age at diagnosis, treatment initiation or study start nor of treatment history in terms of transfusion regimen or iron chelation; (ii) followed patients treated with either desferrioxamine administered subcutaneously or intravenously or oral deferiprone; and (iii) measured hepatic iron concentrations to evaluate treatment efficacy.
The literature on desferrioxamine and deferiprone lacks consensus on their comparative effectiveness and even on the methods for its quantification.
In the first study, 144 patients with thalassemia major and relatively low serum ferritin concentrations (1,500 - 3,000 ng/mL) were randomized to either deferiprone (n = 71) or desferrioxamine (n = 73) and followed for one year [ 28 ] . Although, the primary efficacy measure was the reduction of serum ferritin, HIC was assessed in a small subgroup of patients willing to undergo repeat liver biopsy: 21 in the deferiprone and 15 in the desferrioxamine group.
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