Example sentences for: dermenkephalin

How can you use “dermenkephalin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We examined the effect of dermenkephalin, a specific δ-opioid agonist, in order to mimic the effect of a strong and constant activation by an agonist, on the distribution of the δ-opioid receptors, in the dorsal horn of the rat spinal cord.

  • The two experimental groups received intrathecally 10 μl of a mixture containing 10 μM of thiorphan and 20 μM of kelatorphan (to delay the degradation of the peptide ligand) and 10 μM of dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH 2 , Sigma, a selective δ agonist ( 14, 34)), in 0.9% NaCl.

  • In this study, we provide morphological evidence that δ-opioid receptors are endocytosed in response to dermenkephalin in vivo . The choice of dermenkephalin as agonist in this study was determined by the intrinsic quality of this ligand.

  • without dermenkephalin), no modification of the δ-opioid receptor distribution was noted compared with our control rats (receiving only NaCl).

  • This suggests that the effect observed after dermenkephalin application, associated with the peptidase inhibition, is probably stronger than the potency of dermenkephalin alone.


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