Example sentences for: dermenkephalin

How can you use “dermenkephalin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The two experimental groups received intrathecally 10 μl of a mixture containing 10 μM of thiorphan and 20 μM of kelatorphan (to delay the degradation of the peptide ligand) and 10 μM of dermenkephalin (Tyr-D-Met-Phe-His-Leu-Met-Asp-NH 2 , Sigma, a selective δ agonist ( 14, 34)), in 0.9% NaCl.

  • without dermenkephalin) in NaCl for 15 and 30 minutes to check if the endogenous enkephalins protected by kelatorphan and thiorphan could, by themselves, induce receptor internalization.

  • without dermenkephalin), no modification of the δ-opioid receptor distribution was noted compared with our control rats (receiving only NaCl).

  • Our findings demonstrate that dermenkephalin, after in vivo administration, can induce an internalization of the δ-opioid receptor at the level of the spinal cord.

  • Considering our experimental conditions, particularly using a single in vivo injection, the dermenkephalin seemed the most suitable agonist ligand to specifically stimulate the δ-opioid receptor and provoke a possible internalization of the receptor due to its affinity as well as to its strong resistance to degradation.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast