Words similar to derepression
Example sentences for: derepression
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The observed derepression of Mig1p and Ume6p targets in stationary phase is consistent with the nuclear export of the Mig1p repressor under glucose limitation, as well as recent findings that carbon source genes can be Ume6p targets [ 41 ] . In addition, genes containing a conserved sequence similar to the consensus for Msn2/4p, an inducer of the environmental stress response, and the heat-shock transcription factor Hsf1p were significantly induced under heat shock.
Genetic screens have identified a large number of genes, named SNF (Sucrose Non-Fermenting) that are required for derepression of SUC2 transcription in the absence of glucose [ 16, 17, 18].
The presence of trpR implies that the tryptophan operon is under repression control by L-tryptophan, and some experimental evidence does indeed show derepression under conditions of tryptophan limitation [ 43].
In general, multiple mutations caused greater derepression, up to 79-fold for the triple mutant, nrg1Δ mig1Δ mig2Δ (Figure 3A).
Starvation for host-derived L-tryptophan, which is initiated by induction of indoleamine dioxygenase by IFN-γ, undoubtedly triggers derepression of the entire tryptophan operon, including the genes encoding PRPP synthase and kynureninase.