Words similar to deregulated
Example sentences for: deregulated
How can you use “deregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus in these cases, promoter hypermethylation is one mechanism whereby gene expression can be deregulated in GCTs.
Overexpression of eIF4E leads to deregulated growth and malignant transformation of a variety of cultured cell lines [ 12 13 14 ] . Moreover, elevated levels of eIF4E are commonly found in solid tumors, especially in breast, colon, and head and neck tumors [ 15 ] . Clinical studies indicate that eIF4E gene amplification and protein overexpression is associated with malignant progression in these tumors [ 16 ] . High eIF4E levels are also associated with a higher rate of cancer recurrence and cancer-related death [ 17 ] . In contrast to eIF4E, overexpression of 4EBP inhibits cell proliferation [ 18 ] and 4EBP-1 expression levels are inversely correlated with the progression of certain types of tumors [ 19 ] .
All three human isoforms of AKT have been found to be deregulated in human breast cancer cells [ 32, 33, 34].
Although the genes tested so far showed no deregulated expression, it remains to be seen whether any of these genes or the others mapped to the minimal deleted regions are targets of mutations in CC.
Due to the interconnectivity and interdependency of the electric power grid, information sharing is a necessity for (1) maintaining the reliability of the power supply and (2) conducting business transactions in a deregulated environment.
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