Example sentences for: deregulated

How can you use “deregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Overexpression of eIF4E leads to deregulated growth and malignant transformation of a variety of cultured cell lines [ 12 13 14 ] . Moreover, elevated levels of eIF4E are commonly found in solid tumors, especially in breast, colon, and head and neck tumors [ 15 ] . Clinical studies indicate that eIF4E gene amplification and protein overexpression is associated with malignant progression in these tumors [ 16 ] . High eIF4E levels are also associated with a higher rate of cancer recurrence and cancer-related death [ 17 ] . In contrast to eIF4E, overexpression of 4EBP inhibits cell proliferation [ 18 ] and 4EBP-1 expression levels are inversely correlated with the progression of certain types of tumors [ 19 ] .

  • In the 1996 act it deregulated them again.

  • p107 has been shown to be required for exit from the cell cycle [ 39 40 ] , and reduced p107 expression is associated with deregulated proliferation.

  • Although the genes tested so far showed no deregulated expression, it remains to be seen whether any of these genes or the others mapped to the minimal deleted regions are targets of mutations in CC.

  • Evidence suggests that gain of function in PAX7 triggers neoplastic development by maintaining cells in a deregulated, undifferentiated and proliferative state, as is seen in alveolar rhabdomyosarcomas.


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