Words similar to delta-

Example sentences for: delta-

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Here we took advantage of the fact that dlA dx2 mutant zebrafish embryos survive several days after onset of neuronal differentiation to investigate how Delta-Notch signaling influences neural cell fate.
Together with the above BrdU results, these observations indicate that disruption of Delta-Notch signaling causes excess neural precursors to be specified for early-born neuronal fates at the expense of later-born neuronal and glial fates, without interfering with mechanisms that specify early-born neuronal identity along the dorsoventral axis.
We propose that in the zebrafish central nervous system cell-cell interactions, mediated by Delta-Notch signaling, help coordinate transition of proliferative precursors to specified neurons and glia.
In this view, Delta-Notch signaling diversifies neural cell fate by guiding the orderly, and prolonged, transition from neural precursor cells to specified cells.
To further test the role of Delta-Notch mediated lateral inhibition in zebrafish neurogenesis, we examined embryos homozygous for a missense mutation of dlA ( dlA dx2 ). We previously described the effect of this mutation on development of floorplate, notochord and hypochord [ 37] and dorsal spinal sensory neurons and neural crest [ 38].