Words similar to delta-

Example sentences for: delta-

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We previously showed that disruption of Delta-Notch signaling, by injection of RNA encoding a dominant negative form of frog Delta-1 protein into early cleavage stage zebrafish embryos, caused formation of excess early-specified primary motor neurons and reduced numbers of later-specified secondary motor neurons [ 28].
We propose that in the zebrafish central nervous system cell-cell interactions, mediated by Delta-Notch signaling, help coordinate transition of proliferative precursors to specified neurons and glia.
These observations support the idea that Delta-Notch mediated lateral inhibition coordinates transition of proliferative neural precursors into specified neurons and glia of the spinal cord.
To further test the role of Delta-Notch mediated lateral inhibition in zebrafish neurogenesis, we examined embryos homozygous for a missense mutation of dlA ( dlA dx2 ). We previously described the effect of this mutation on development of floorplate, notochord and hypochord [ 37] and dorsal spinal sensory neurons and neural crest [ 38].
Mutant and gene overexpression phenotypes in various vertebrate model systems support the notion that Delta-Notch signaling mediates lateral inhibition in the central nervous system [ 16, 20, 24, 25, 26, 27, 28, 29, 35].