Words similar to dek
Example sentences for: dek
How can you use “dek” in a sentence? Here are some example sentences to help you improve your vocabulary:
Once again, the A-to-G substitution at position 3 in the Y box appears to strengthen DEK binding to the DQA1 Y box in comparison with the DRA Y box; allelic variation in the nucleotide at position 7 in the Y-box sequence (as in DQA1*0501 and in the DR4-associated
bp = base pair(s); EMSA = electrophoretic mobility shift assay; FLAG = Five NH 2 -terminally deleted epilope; MHC = Major histocompatibility complex; HIV = human immunodeficiency virus; JRA = juvenile rheumatoid arthritis; K d[app] = apparent dissociation constant; PCR = polymerase chain reaction; pets = peri- ets ; rDEK = recombinant DEK protein.
Three specific findings in this report support a potential role for DEK as a transcriptional modulator of MHC class II expression.
Recombinant protein was purified from bacterial lysates in accordance with the published method for the QIA express system (Qiagen, Valencia, CA, USA) with variations in Buffers B and D as noted in Additional file: 1. Procedures were carried out at 4°C; dialyzed recombinant DEK protein (rDEK) was stored at -80°C.
Having established that DEK and NF-Y in nuclear extracts participate in the HLA-DQA1*0101 binding complex, we used recombinant full-length DEK (rDEK) to determine whether it alone can bind to Y-box motifs and to examine how gene- and allele-specific sequence polymorphisms alter its binding.
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