Words similar to dek
Example sentences for: dek
How can you use “dek” in a sentence? Here are some example sentences to help you improve your vocabulary:
In this study, we examine the characteristics of DEK binding to the Y-box sequences of DQA1*0101, DQA1*0501, DRA, DQB , and DRB . We also confirm participation of DEK with NF-Y in the DQA1 Y-box binding complex and localize specific DEK binding within this sequence.
Quantification of the apparent dissociation constant (K d[app] ) for rDEK binding to related class II MHC Y-box motifs validates the relative hierarchy of DEK binding activity described above, and further emphasizes the contribution of gene-specific Y-box polymorphisms to DEK binding activity.
1) first led us to investigate whether DEK in nuclear extracts binds to MHC class II Y-box regulatory elements in vitro . With a double-stranded oligonucleotide probe containing the HLA-DQA1*0101 Y-box sequence, EMSAs revealed similar binding activity in nuclear extracts from B lymphoid (Namalwa), T lymphoid (Jurkat, CEM), monocytoid (U937), and HeLa cell lines (Fig.
Children with pauciarticular-onset JRA were also significantly more likely to have anti-DEK antibodies than were children with polyarticular-onset or systemic-onset JRA or other rheumatic diseases.
Consistent protection is also seen at position 2, adjacent to the A-for-G substitution that diverges from the Y-box consensus sequence, although there is no protection of the divergent base itself at position 3. DNase I protection by recombinant DEK extends over the length of the Y-box sequence, including bases within the NF-Y binding site (reverse CCAAT sequence), again suggesting that the two proteins may interact.
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