Example sentences for: dek

How can you use “dek” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Once again, the A-to-G substitution at position 3 in the Y box appears to strengthen DEK binding to the DQA1 Y box in comparison with the DRA Y box; allelic variation in the nucleotide at position 7 in the Y-box sequence (as in DQA1*0501 and in the DR4-associated

  • bp = base pair(s); EMSA = electrophoretic mobility shift assay; FLAG = Five NH 2 -terminally deleted epilope; MHC = Major histocompatibility complex; HIV = human immunodeficiency virus; JRA = juvenile rheumatoid arthritis; K d[app] = apparent dissociation constant; PCR = polymerase chain reaction; pets = peri- ets ; rDEK = recombinant DEK protein.

  • Three specific findings in this report support a potential role for DEK as a transcriptional modulator of MHC class II expression.

  • Recombinant protein was purified from bacterial lysates in accordance with the published method for the QIA express system (Qiagen, Valencia, CA, USA) with variations in Buffers B and D as noted in Additional file: 1. Procedures were carried out at 4°C; dialyzed recombinant DEK protein (rDEK) was stored at -80°C.

  • Having established that DEK and NF-Y in nuclear extracts participate in the HLA-DQA1*0101 binding complex, we used recombinant full-length DEK (rDEK) to determine whether it alone can bind to Y-box motifs and to examine how gene- and allele-specific sequence polymorphisms alter its binding.


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