Example sentences for: dek

How can you use “dek” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 4, lane 5), leaving a residual band (arrow) which can be attributed to distinct DEK binding activity.

  • bp = base pair(s); EMSA = electrophoretic mobility shift assay; FLAG = Five NH 2 -terminally deleted epilope; MHC = Major histocompatibility complex; HIV = human immunodeficiency virus; JRA = juvenile rheumatoid arthritis; K d[app] = apparent dissociation constant; PCR = polymerase chain reaction; pets = peri- ets ; rDEK = recombinant DEK protein.

  • Another is that NF-Y and DEK both participate in the HLA-DQA*0101 Y-box binding complex, which coordinates DQ protein expression.

  • We have previously shown that activation of promyeloid cells causes dephosphorylation of DEK and diminished DEK binding to the HIV-2 long terminal repeat [ 16 17 32 ] . In this study, we show that rDEK can bind to the DQA1 Y box, and that DEK in nuclear extracts participates in the DQA1 Y-box binding complex in vitro . Thus, we propose a model in which intracellular signaling modulates the ability of DEK to bind DNA, causing alteration of MHC class II transcription.

  • Development of antibodies to DEK could even be a primary event in the pathogenesis of JRA, with disruption of nuclear events due to penetration of anti-DEK antibodies into living cells [ 35 ] . It remains to be determined whether anti-DEK antibodies are directly involved in the pathogenesis of autoimmune disease, or if they result from generally enhanced immunoreactivity.


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