Words similar to dek
Example sentences for: dek
How can you use “dek” in a sentence? Here are some example sentences to help you improve your vocabulary:
Both DEK and NF-Y participate in the HLA-DQA1Y-box binding complex
1) first led us to investigate whether DEK in nuclear extracts binds to MHC class II Y-box regulatory elements in vitro . With a double-stranded oligonucleotide probe containing the HLA-DQA1*0101 Y-box sequence, EMSAs revealed similar binding activity in nuclear extracts from B lymphoid (Namalwa), T lymphoid (Jurkat, CEM), monocytoid (U937), and HeLa cell lines (Fig.
Further characterization of rDEK binding to the polymorphic DQA1*0501 Y-box sequence and to the consensus ( HLA-DRA ) Y-box sequence establishes a relative hierarchy of DEK binding activity (Fig.
The same electrophoretic patterns were seen after preincubation of nuclear extracts from the CEM T lymphocytoid cell line with anti-DEK and anti-NF-YA antibodies (data not shown).
Consistent protection is also seen at position 2, adjacent to the A-for-G substitution that diverges from the Y-box consensus sequence, although there is no protection of the divergent base itself at position 3. DNase I protection by recombinant DEK extends over the length of the Y-box sequence, including bases within the NF-Y binding site (reverse CCAAT sequence), again suggesting that the two proteins may interact.
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