Example sentences for: deferiprone

How can you use “deferiprone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The analysis presented here casts doubt, however, even on this premise that deferiprone offers a useful alternative to desferrioxamine in patients who have difficulties with the administration of a parenteral drug.

  • We undertook a quantitative review of the literature to estimate the effectiveness of desferrioxamine and deferiprone in decreasing hepatic iron concentrations (HIC) in thalassemia major.

  • In the first study, 144 patients with thalassemia major and relatively low serum ferritin concentrations (1,500 - 3,000 ng/mL) were randomized to either deferiprone (n = 71) or desferrioxamine (n = 73) and followed for one year [ 28 ] . Although, the primary efficacy measure was the reduction of serum ferritin, HIC was assessed in a small subgroup of patients willing to undergo repeat liver biopsy: 21 in the deferiprone and 15 in the desferrioxamine group.

  • Indeed, to our knowledge, only one randomized controlled trial comparing desferrioxamine and deferiprone has been conducted and results for that study are incomplete as the trial was terminated prematurely and has not been reported in full [ 9 10 11 ] .

  • The doses of deferiprone - even in the optimal dose group - are relatively low, compared to the desferrioxamine doses, which in most studies are well above the recommended 40 mg/kg/day.


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