Example sentences for: deferiprone

How can you use “deferiprone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The most recent of these reviews also corroborate our finding that deferiprone-treated patients do not experience the same degree of improvement in hepatic iron levels as desferrioxamine-treated patients [ 2 6 ] and some project further doubt on the long-term implications of deferiprone treatment [ 8 ] .

  • A case-control study in 15 patients treated with deferiprone (cases) and 30 patients treated with desferrioxamine (controls) matched for age and serum ferritin levels, demonstrated that deferiprone appears to be more effective than desferrioxamine in removal of myocardial iron despite significantly higher HIC in the deferiprone group [ 5 ] . Although a larger prospective trial is needed to confirm the results, these findings would suggest that a combination of both drugs may be most beneficial in order to reduce both hepatic and myocardial concentrations of iron.

  • On the other hand, the results from the only randomized trial suggest that even at relatively low doses, desferrioxamine outperforms deferiprone [ 11 ] . Moreover, the toxic:therapeutic ratio of deferiprone is reportedly low; doses of 100 mg/kg/day have resulted in bone marrow toxicity in animals and humans.

  • 4 mg/g) in deferiprone optimal dose and 33.

  • Patients in the study conducted by Diav-Citrin [ 22 ] were all treated with deferiprone and we defined improvement as HIC that were reduced or maintained at less than 7 mg/g of dry weight liver tissue.


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