Words similar to deferiprone
Example sentences for: deferiprone
How can you use “deferiprone” in a sentence? Here are some example sentences to help you improve your vocabulary:
A threshold of 15 mg/g tissue iron had to be used instead for the comparative study conducted by Olivieri and colleagues due to how these researchers summarize the results [ 11 ] . For the study by Longo and colleagues [ 18 ] , patients receiving deferiprone who were in a negative or stable iron balance at the end of the observation period were considered to have improved.
It has been said that a meta-analysis is only useful until the next good trial comes along [ 29 ] . In the case of iron chelation therapy for patients with thalassemia major, the addition of any good prospective randomized control trial documenting the impact of treatment on body iron (hepatic and/or myocardial) would contribute measurably to the evaluation of the long-term implications of treatment with deferiprone, compared to desferrioxamine.
The National Library of Medicine's computerized bibliographic database (Medline 1966 to December 1999) was searched using a combination of the following keywords: thalassemia, serum ferritin, urinary iron excretion, hepatic iron, liver, chelation therapy, iron chelation, iron chelating agents, desferal, desferrioxamine, deferoxamine, L1 oral chelate, deferiprone and 1,2-dimethyl-3-hydroxypyrid-4-one.
The doses of deferiprone - even in the optimal dose group - are relatively low, compared to the desferrioxamine doses, which in most studies are well above the recommended 40 mg/kg/day.
Indeed, to our knowledge, only one randomized controlled trial comparing desferrioxamine and deferiprone has been conducted and results for that study are incomplete as the trial was terminated prematurely and has not been reported in full [ 9 10 11 ] .
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