Words similar to deferiprone

Example sentences for: deferiprone

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Patients in the study conducted by Diav-Citrin [ 22 ] were all treated with deferiprone and we defined improvement as HIC that were reduced or maintained at less than 7 mg/g of dry weight liver tissue.
The National Library of Medicine's computerized bibliographic database (Medline 1966 to December 1999) was searched using a combination of the following keywords: thalassemia, serum ferritin, urinary iron excretion, hepatic iron, liver, chelation therapy, iron chelation, iron chelating agents, desferal, desferrioxamine, deferoxamine, L1 oral chelate, deferiprone and 1,2-dimethyl-3-hydroxypyrid-4-one.
7 mg/g) in deferiprone low dose (overall p < 0.01; findings confirmed in pairwise comparisons).
In the first study, 144 patients with thalassemia major and relatively low serum ferritin concentrations (1,500 - 3,000 ng/mL) were randomized to either deferiprone (n = 71) or desferrioxamine (n = 73) and followed for one year [ 28 ] . Although, the primary efficacy measure was the reduction of serum ferritin, HIC was assessed in a small subgroup of patients willing to undergo repeat liver biopsy: 21 in the deferiprone and 15 in the desferrioxamine group.
The analysis presented here casts doubt, however, even on this premise that deferiprone offers a useful alternative to desferrioxamine in patients who have difficulties with the administration of a parenteral drug.