Example sentences for: deferiprone

How can you use “deferiprone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Despite the fact that compliance is improved on deferiprone, this highlights the dangers of assuming that this drug, with potential toxicity greater than that of desferrioxamine, should be implemented in patients struggling with desferrioxamine, as proposed by some clinicians.

  • To many, deferiprone may not appear as a first-line chelator but rather as an alternative to desferrioxamine should the latter not be usable.

  • The doses of deferiprone - even in the optimal dose group - are relatively low, compared to the desferrioxamine doses, which in most studies are well above the recommended 40 mg/kg/day.

  • The analysis presented here casts doubt, however, even on this premise that deferiprone offers a useful alternative to desferrioxamine in patients who have difficulties with the administration of a parenteral drug.

  • In the first study, 144 patients with thalassemia major and relatively low serum ferritin concentrations (1,500 - 3,000 ng/mL) were randomized to either deferiprone (n = 71) or desferrioxamine (n = 73) and followed for one year [ 28 ] . Although, the primary efficacy measure was the reduction of serum ferritin, HIC was assessed in a small subgroup of patients willing to undergo repeat liver biopsy: 21 in the deferiprone and 15 in the desferrioxamine group.


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