Words similar to decarboxylase
Example sentences for: decarboxylase
How can you use “decarboxylase” in a sentence? Here are some example sentences to help you improve your vocabulary:
The cell surface expressed integrins can control this process by physically interacting with the extracellular matrix proteins and other cell surface proteins on endothelial cells lining the blood vessel wall [ 1 ] . These integrins signal adhesion and migration by communicating with several tyrosine kinases inside the cell, including the Focal Adhesion Kinase (FAK) and Src family kinases [ 1 2 ] . Src kinases control the activation of FAK, as well as the tyrosine phosphorylation of critical substrates that regulate adhesion and migration [ 3 ] . Indeed, colon cancer cells with high metastatic potential have elevated levels of Src activity or activating mutations in the Src gene [ 4 5 ] . One Src substrate that is involved in regulating an important signaling node in this process is the adaptor protein p130 cas (Cas) [ 6 7 8 9 10 ] . Cas appears to play a central role in the transformation process by several oncogenes including ras, ornithine decarboxylase (ODC), v-Src, v-crk, and Bcr-Abl, as these tumors all have elevated levels of tyrosine phosphorylated Cas [ 6 11 12 13 ] . Cells from mice that lack Cas have much reduced migration and are resistant to transformation by v-Src, while expression of Cas anti-sense RNA in cells transformed with ras, v-Src or ODC result in reversion of the transformed phenotype [ 11 14 15 ] . Furthermore, increased expression of Cas can rescue cell migration and adhesion in cells expressing the tumor suppressor PTEN, and can enhance cell migration and adhesion in normal cells, with a major role being played by the substrate domain [ 16 17 ] .
For example, the complementary sequence shared between Dopa decarboxylase and CG10561 is thought to be involved in regulating the levels of these transcripts [ 45].
2 μM (vaccinia), 27 μM (monkeypox) and 58 μM (cowpox) [ 40 41 ] . Other classes of compounds have been tested for their effectiveness against vaccinia virus including the IMP dehydrogenase inhibitors (EC 50 4 - 100 μg/mL), OMP decarboxylase inhibitors (0.
Some of these involve overlapping messages that have been previously described (for example, Dopa decarboxylase and CG10561 [ 45]); however, the vast majority were not previously known to overlap.
The best-characterized example of ubiquitin-independent degradation is the degradation of ornithine decarboxylase (ODC), which is dependent upon ODC interaction with the targeting protein antizyme (Az) [ 18 ] . How ubiquitinated substrates or Az-bound ODC is recognized by the 26S proteasome is not well understood.
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