Words similar to decarboxylase
Example sentences for: decarboxylase
How can you use “decarboxylase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Some of these involve overlapping messages that have been previously described (for example, Dopa decarboxylase and CG10561 [ 45]); however, the vast majority were not previously known to overlap.
They are: two ubiquitin precursors UBA80 (clone 1) and UBA52 (clone 21), the ornithine decarboxylase antizyme (Az) (clone 15) and the proteasome β subunit HsN3 (clone 18).
Many genes that are known to amplify in response to selection, primarily during anticancer drug treatments, were found to be present in multiple copies in mammalian genomes as well, in particular, aminoacyl-tRNA synthetases, glutamine synthetase and other anabolic enzymes, adenosine deaminase, ornithine decarboxylase, AMP deaminase, and N -acetyl glucosaminyltransferase [ 34, 46].
The best-characterized example of ubiquitin-independent degradation is the degradation of ornithine decarboxylase (ODC), which is dependent upon ODC interaction with the targeting protein antizyme (Az) [ 18 ] . How ubiquitinated substrates or Az-bound ODC is recognized by the 26S proteasome is not well understood.
The 26S proteasome is responsible for the bulk turnover of cytoplasmic and nuclear proteins in eukaryotic cells and also plays a key role in the regulation of cell cycle, signal transduction, transcription as well as antigen presentation [ 17 18 19 20 21 ] . Most of the known proteasomal substrates are marked and targeted to proteasome by ubiquitination [ 17 19 20 ] . Ubiquitination, however, is not an obligatory step for substrate targeting to proteasome [ 17 18 20 ] . The degradation of the ornithine decarboxylase (ODC), the rate-limiting enzyme for polyamine synthesis, involves a protein named antizyme (Az), which binds and targets ODC to 26S proteasome for degradation [ 18 ] . However, ODC has remained an "orphan" in Az-dependent proteasomal degradation.
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