Words similar to deab

Example sentences for: deab

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DEAB was first used to sensitize the mouse leukemic cell line L1210/CPA, which is resistant to 4-hydroperoxycyclophosphamide (4-HC) by virtue of its overexpression of ALDH1A1.
With co-exposures to 1 μM retinal and up to 50 μM DEAB or DPAB, HL-60 differentiation was inhibited by only 30% after 144 hours of exposure, compared with cells exposed to retinal alone (Figure 2) DPAB did not alter the induction of differentiation by retinoic acid, nor did it affect cell viability up to 144 hours.
By day 6, less than 1% of the retinal was oxidized to retinoic acid, suggesting that non-enzymatic formation or serum-mediated formation of retinoic acid was not responsible for the observed differentiation in cells exposed to DEAB or DPAB.
Cells were exposed to combinations of 1 μM retinoic acid, 1 μM retinal, and various concentrations of DPAB and DEAB prepared in sterile dimethyl sulfoxide (DMSO) or ethanol.
Although DPAB is a more potent inhibitor of human ALDH1A1 than DEAB, we were concerned that DPAB was not remaining in solution at 50 μM in the culture media.