Words similar to de-localization

Example sentences for: de-localization

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The sensitivity of the leading edge is demonstrated by the observation that DMSO treatment at a concentration of 1% causes temporary inhibition of ruffling and concomitant Arp3 de-localization (Yarrow unpublished results).
Our data are consistent with results in sea urchin coelomocytes where BDM phenocopies the effect of cytochalasin D, blocking retrograde flow at the leading edge with continued contraction of the actin network causing a clearing of actin at the leading edge [ 11 ] . In the coelomyocte system, de-localization of leading edge components by BDM could account for the inhibition of actin polymerization and clearing.
We observe that within two minutes, application of BDM leads to the de-localization of the leading edge components - Arp3, VASP, and WAVE - and this is concurrent with the loss of the actin network at the leading edge.
After BDM treatment, we observed a uniform decrease in fluorescence suggestive of dissociation and diffusion of Arp3, rather than de-localization driven by retrograde flow [Figure 5A].
Data from studies of in vivo and in vitro filopodia formation suggest that they develop as a reorganization of the dendritic network in which they exist [ 29 30 ] . In the presence of proteins that bundle and reorganize actin filaments into filopodial precursors, the de-localization of Arp2/3 and other leading edge components may lead to the formation of filopodia, which are then elongated as described above.