Example sentences for: de-localization

How can you use “de-localization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Two possible mechanisms for Arp2/3 complex de-localization were considered: Arp2/3 could move back from the leading edge with retrograde flow of actin and then be lost from the filaments, or it could simply diffuse from the leading edge.

  • The sensitivity of the leading edge is demonstrated by the observation that DMSO treatment at a concentration of 1% causes temporary inhibition of ruffling and concomitant Arp3 de-localization (Yarrow unpublished results).

  • In all cases, the loss of Arp3-GFP at the leading edge was seen concomitantly with loss of ruffling and retraction of the leading edge or as de-localization with slight retraction.

  • Data from studies of in vivo and in vitro filopodia formation suggest that they develop as a reorganization of the dendritic network in which they exist [ 29 30 ] . In the presence of proteins that bundle and reorganize actin filaments into filopodial precursors, the de-localization of Arp2/3 and other leading edge components may lead to the formation of filopodia, which are then elongated as described above.

  • After BDM treatment, we observed a uniform decrease in fluorescence suggestive of dissociation and diffusion of Arp3, rather than de-localization driven by retrograde flow [Figure 5A].


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