Example sentences for: dcm

How can you use “dcm” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The extent andoccurrence of apoptosis may partially explain the lack of an overallincrease in heart weight in hearts from non-treated DCM animals,despite a pronounced increase in heart size.

  • In addition to DCM with conduction system disease and variable skeletal muscle involvement, mutations in the Lamin A/C gene [OMIM 150330] have been shown to cause autosomal dominant [ 11 ] and autosomal recessive [ 12 ] Emery-Dreifuss Muscular Dystrophy (EDMD), autosomal dominant limb-girdle muscular dystrophy type 1B (LGMD) [ 13 ] , autosomal recessive type 2 Charcot-Marie Tooth type 2 [ 14 ] , familial partial lipodystrophy [ 15 16 ] , Mandibuloacral dysplasia [ 17 ] and Hutchinson-Gilford progeria [ 18 ] . The phenotypic spectrum from DCM to EDMD and limb girdle muscular dystrophy appears continuous.

  • In vivo contractile performance of the heart was assessed bythe determination of fractional shortening of the left ventricle.As shown in Table 1and Figure 1, fractional shortening was increasedby 32 and 45% in DCM 1 and DCM 20 animals, respectively,compared to non-treated DCM animals (DCM 0 ). Comparedwith baseline values at the time of randomization, the improvementin fractional shortening was of 57% in DCM 1 and 65% inDCM 20 . Associated with improved cardiac function wasa reduction in the incidence of apoptotic nuclei (see below).

  • We have previously shown that removal of furazolidone from thefeed after three weeks results in progressive cardiac dilatationand heart failure [ 18 ] . At the time ofrandomization of the DCM group into three groups i.e., DCM 0 (notreatment), DCM 1 (lower dose carvedilol) or DCM 20 (higherdose carvedilol), fractional shortening was not different betweenthe groups (p > 0.1).

  • 2 locus [ 9 ] . Mutations in the LMNA gene associated with DCM have a more severe prognosis and higher-event rates compared to individuals with DCM that do not have LMNA mutations [ 20 ] . A recent report describing another family with a LMNA mutation causing DCM and conduction system disease documents the need for permanent pacemaker implantation [ 21 ] . Previous reports on the proband's kindred support a high-event rate in family members often resulting in sudden cardiac death even in family members with permanent pacemakers [ 10 ] . For example, ten out of 38 family members with pacemakers for high-grade atrioventricular block died suddenly.


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