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Example sentences for: dayhoff
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Distances between aligned proteins were estimated with the Dayhoff amino-acid replacement model [ 51 ] . Tree topologies were then inferred from these distances via neighbor-joining [ 52 ] and 1,000 non-parametric bootstrap replicates were used to estimate clade support [ 53 ] . Maximum likelihood analysis produced topologies consistent with the neighbor-joining analysis.
For all three possible unrooted tree topologies maximum-likelihood values and posterior probabilities were calculated using in-house JAVA programs that were written utilizing classes from the Phylogenetic Analysis Library version 1.0 [ 54 ] and parts of Vanilla package version 1.0 [ 54 ] . If not indicated otherwise, likelihood values were estimated using the automatically selected suitable substitution model (chosen from BLOSUM62, CPREV, Dayhoff, JTT, MTREV24, VT and WAG) with no ASRV.
The distance matrix was obtained using Protdist with a Dayhoff Pam matrix.
Phylogenetic trees were constructed by first generating a distance matrix using the PROTDIST program and the Dayhoff PAM model for amino-acid substitutions and employing this matrix for minimum evolution (least-square) tree building [ 30] using the FITCH program.
3. Maximum likelihood pairwise distance matrices are calculated for each of the x multiple alignments using a model of amino acid substitution (for example, BLOSUM [ 25 ] or Dayhoff PAM [ 26 ] ).
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