Words similar to cyclo-oxygenase-
Example sentences for: cyclo-oxygenase-
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Triterpenoids are a novel family of steroid-like compounds with weak anti-inflammatory properties [ 18 ] . Synthetic triterpenoids have been produced with the aim of achieving increased potency [ 19 20 ] . 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) is a synthetic triterpenoid that has been shown to inhibit expression of the inflammatory genes inducible nitric oxide synthase and cyclo-oxygenase-2 [ 20 21 22 ] . In a recent report, MMP-1 and MMP-13 expression were induced with IL-1, a known pro-inflammatory mediator in vivo in joint tissues [ 23 ] . It was shown that CDDO could inhibit the IL-1-induced expression of these pro-inflammatory MMPs.