Words similar to cyab
Example sentences for: cyab
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Regular expression searches with the conservation pattern found in these CyaB homologs also recovered the most of the members detected in the above-mentioned profile searches, but failed to recover any new candidates.
The possibility of lateral transfer of Aeromonas CyaB from an archaeal source has been previously suggested, and is consistent with the enzyme being optimally functional under high temperature [ 16 ] . There are 3 distinct CYTH domains in the euryarchaeon Methanosarcina acetivorans , in addition to the version which groups with the CYTH domains that are found, in single or duplicate copies, in other archaea and eukaryotes.
Reciprocal searches initiated with the E. coli YgiF protein (residues 1-200), not only recovered its bacterial orthologs, archaeal CyaB homologs and eukaryotic proteins, but also several others such as Bacillus subtilis YjbK, Methanosarcina Ma2350, and Mesorhizobium loti Mll4592 with e-values in the range of 10 -4-10 -6upon first detection.
Experimental analysis on the Methanococcus CyaB homolog revealed no adenylyl cyclase activity comparable to that seen in Aeromonas CyaB [ 16 ] . Likewise, there is no evidence for a widespread presence of the ThTPase activity in the organisms that contain CYTH domain proteins [ 17 ] . Hence, the principal biological function of the CYTH domains may be different from those of the experimentally characterized members of this family.
In order to understand the evolutionary affinities and provenance of the CyaB adenylyl cyclase from Aeromonas hydrophila , we carried out database searches using sensitive sequence profile analysis methods.
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