Words similar to currents
Example sentences for: currents
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Mutations in TMC1 are responsible for the autosomal dominant human hearing disorder DFNA36 and for the recessive deafness DFNB7/11 [ 5 ] ; the corresponding murine gene Tmc1 also causes deafness in the mutant mouse strains Beethoven ( Bth ) and deafness ( dn ) [ 6 ] . Bth / Bth mice display altered potassium currents in early postnatal cochlear hair cells, in particular Ik,n and Ik,f currents appear to be depressed [ 10 ] . This observation led to the hypothesis that Tmc1 may participate directly or indirectly in regulating the permeability of potassium channels [ 10 ] . Because of the high level of conservation of the amino acid sequences among the eight mammalian TMC proteins (Figure 1, Additional file 1), we speculate that other TMC proteins may as well be modifiers of ion channels or transporters.
The similar values of EC 50 and Hill coefficient of multiple channel currents and single channel currents suggest that the rate constants along the activation pathway had changed in a compensatory way.
There is no question that convection currents move small and even large structures.
“It may be that this coupling between larval krill and ice is actually underpinning the entire question of krill population dynamics,” says Gallager—in which case, understanding how the ice moves relative to the water currents and wind shear over the top will be critical.
Under a condition where ATP concentration in the β-cell was clamped at a constant level, PMA increased tolbutamide-sensitive currents in response to voltage ramps from -90 to -50 mV (Fig.
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