Example sentences for: csn

How can you use “csn” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, CSN deficiency appears to stimulate Pcu3p-associated ubiquitin ligase activity in vitro . A similar stimulation was obtained for substrate-specific polyubiquitylation of phosphorylated Rum1p by SCF Poppurified from csn5 mutants (unpublished observation).

  • However, while mutation of csn5 caused a modest two-fold increase in the steady state fraction of neddylated Pcu3p (Fig.

  • uncovered a novel connection between the COP9/signalosome (CSN) and cullin neddylation [ 10].

  • Future studies will reveal whether some of the other described functions of CSN also involve post-translational modification of regulatory proteins by ubiquitin-like modifiers.

  • Thus, cullin regulation through modulation of the balance of Ned8p modification appears to require the entire CSN complex.


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