Words similar to csn

Example sentences for: csn

How can you use “csn” in a sentence? Here are some example sentences to help you improve your vocabulary:

The CSN complex may, for example, serve as a platform for recruitment of a separate deneddylating enzyme.
Further analysis of the CSN will no doubt uncover additional mechanisms whereby ubiquitin-mediated protein degradation is controlled.
Further experiments are required to determine whether recombinant Csn5p or purified CSN complex can inhibit Pcu3p-associated ubiquitin ligase activity.
2A, and data not shown), also suggests that control of cullin neddylation results from cooperation of multiple CSN components rather than from the activity of a single catalytic subunit.
While our study suggests that SKP2 is an important player in p27 regulation in prostate cancer cells, recent studies have also implicated another protein, CSN5/JAB1, in p27 regulation [ 54 55 ] . CSN5 is a subunit of the COP9/signalosome (CSN) complex [ 56 57 58 59 ] , but also forms distinct complexes apparently lacking CSN subunits [ 55 60 61 62 ] . Overexpression of CSN5 in NIH3T3 cells causes p27 export from the nucleus and ectopic degradation [ 54 ] . Notably, like SKP2 [ 33 36 37 38 ] , CSN5 was found to be overexpressed in cancers devoid of p27 [ 63 ] . However, our studies did not reveal any effect of MIB on CSN5 expression.