Example sentences for: csa

How can you use “csa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recently [ 11 ] , we have demonstrated the efficacy of combination of low doses of SRL with either CsA or TAC to inhibit lymphocyte proliferation.

  • The long-term treatment of patients with either CsA or TAC results in side effects such as nephrotoxicity, hypertension, and gingival hyperplasia [ 1 2 ] . Sirolimus (SRL) a new immunosuppressive agent is structurally similar to TAC binds to same binding protein FKBP, but its mechanism of action is different [ 3 ] . Both clinical and experimental studies demonstrated that SRL when used either with CsA or alone is associated with side effects such as hyperlipidemia, thrombocytopenia and nephrotoxicity [ 4 5 6 7 ] . Since SRL and TAC have affinity for the same binding site, it was thought to be ineffective when used together.

  • These results are consistent with our previous studies [ 21 22 ] , that TGF-β mediates in part the immunosuppressive effects of CsA and TAC.

  • CSA focuses on the totality of government operations rather than on individual programs.

  • Encouraged by our recent in vitro study [ 11 ] that demonstrated a significant inhibition of lymphocyte proliferation, IL-2 and induction of TGF-β expression by combination of sub-clinical concentration of SRL with either TAC or CsA, we conducted the current study on renal transplant recipients.


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