Words similar to crac
Example sentences for: crac
How can you use “crac” in a sentence? Here are some example sentences to help you improve your vocabulary:
In order to evaluate whether Btk:ER-induced calcium mobilization was due to calcium release from internal stores or calcium influx across cell membrane calcium release activated channels (CRAC), cells were pre-treated with EGTA to chelate extracellular calcium (Fig 2D; note change in scale within Fig.
The coordinated vitamin D-dependent induction of the cytosolic calcium-binding protein calbindin D could serve this function when the need for transcellular calcium flux is high by acting directly or indirectly as a molecular sponge and selectively removing calcium ions from the CaT1 channel and/or to buffer increases in intracellular calcium, thereby preventing premature inactivation of this I CRAC channel [ 15 ] . Calbindin D could also play its traditionally conceived role as a calcium chaperone protein to facilitate the transfer of calcium through the cytosol [ 32 ] and perhaps delivery of Ca ++to the basolateral ATP-dependent calcium pump for extrusion out of the enterocyte [ 33 ] .
The CaT1 channel has been recently expressed in mammalian CHO cells and patch clamp studies have shown it to have the characteristics of I CRAC [ 15 ] . Nearly ubiquitous, store-operated calcium entry is essential in a wide variety of cellular processes including muscle contraction, protein secretion, metabolism, cell differentiation, cell division and apoptosis [ 14 ] .
These data argue against the possibility that Btk:ER directly controls a CRAC.
This suggests that Btk:ER may induce calcium release from intracellular stores which subsequently results in calcium influx across CRAC.
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