Words similar to cpt
Example sentences for: cpt
How can you use “cpt” in a sentence? Here are some example sentences to help you improve your vocabulary:
We used CPT, an inhibitor of topoisomerase I, that is a well defined apoptogenic agent belonging to a promising class of antineoplastic drugs [ 23 ] . In contrast to more physiological stimuli (i.e, oxidative stress) induction of apoptosis by CPT is less complex and thus is a better model for study of MP-release phenomenon.
Clinically approved Topo I inhibitors, irinotecan and topotecan, are semisynthetic derivatives of CPT that differ from CPT in toxicity profiles and water solubility but not in the mechanisms of action [ 16, 17].
Similarly, induction of apoptosis with 5 μM CPT, a topoisomerase I inhibitor [ 19 ] , led to a release of annexin V-binding MP which was prevented by ZVAD.
The malonyl CoA generated in the ACC reaction then inhibits FA oxidation by reversibly inhibiting Cpt1.
To our surprise, in CPT treated HUVEC the MP-release did not correlate with the extent cell desquamation and apoptosis or remaining adherent cells characterized by PS exposure on the cell membrane and DNA-fragmentation (TUNEL) (Fig.