Example sentences for: cpt

How can you use “cpt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We used CPT, an inhibitor of topoisomerase I, that is a well defined apoptogenic agent belonging to a promising class of antineoplastic drugs [ 23 ] . In contrast to more physiological stimuli (i.e, oxidative stress) induction of apoptosis by CPT is less complex and thus is a better model for study of MP-release phenomenon.

  • Clinically approved Topo I inhibitors, irinotecan and topotecan, are semisynthetic derivatives of CPT that differ from CPT in toxicity profiles and water solubility but not in the mechanisms of action [ 16, 17].

  • Similarly, induction of apoptosis with 5 μM CPT, a topoisomerase I inhibitor [ 19 ] , led to a release of annexin V-binding MP which was prevented by ZVAD.

  • The malonyl CoA generated in the ACC reaction then inhibits FA oxidation by reversibly inhibiting Cpt1.

  • To our surprise, in CPT treated HUVEC the MP-release did not correlate with the extent cell desquamation and apoptosis or remaining adherent cells characterized by PS exposure on the cell membrane and DNA-fragmentation (TUNEL) (Fig.


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