Words similar to cpg
Example sentences for: cpg
How can you use “cpg” in a sentence? Here are some example sentences to help you improve your vocabulary:
The increased density of CpG islands in R bands was more striking (59%), whereas GC content was only a few percent higher (42.
A nonrandom pattern of promoter hypermethylation has been noted in specific genes in specific tumor types, although some genes are commonly methylated in diverse tumors [ 3 4 ] . The extent of aberrant promoter hypermethylation and its association with loss of gene function in cancer suggests that CpG island methylation is an important mechanism in inactivating tumor suppressor genes (TSGs).
60% of the 5' ends of known genes on chromosome 22 are located within CpG islands, regions in the genome that are not depleted of CG dinucleotides and are associated with an open chromatin structure [ 38].
Short spikes of CpG islands (for example, in 3p26 and 3p25 of Figure 1) do not obviously appear in the assay, perhaps because they are below the resolution of FISH or are part of transcriptionally active regions.
Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment with the hypo-methylating agent 5-aza-2'-deoxycytidine and HDAC-inhibiting agent n-butyrate in a dose and duration-dependent manner.
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