Words similar to cpg
Example sentences for: cpg
How can you use “cpg” in a sentence? Here are some example sentences to help you improve your vocabulary:
MeCP2's functional structure consists of an 84 amino acid methyl-binding domain (MBD) [ 11 ] and a 104 amino acid transcriptional repression domain (TRD) [ 12 ] . The MBD is able to bind to 5-methyl cytosine residues of a single CpG dinucleotide [ 11 ] . Under the current model, MeCP2 binds to DNA, then complexes with Sin3A through the TRD and recruits histone deacetylases (HDAC).
Alternatively, while MeCP2's expression is ubiquitous, other methyl-CpG binding proteins that exist within complexes, MBD1 and MBD2 [ 19 ] or Kaiso [ 20 ] , may reduce the effect of mutations in MECP2 in peripheral organ systems while the lack of such redundancy may lead to a more pronounced phenotype in the brain.
LINE1 elements again differed from other features, showing a negative correlation with exons, CpG islands, GC content and Alu repeats.
The MSP method detects only methylation of full-length CpG islands and cannot identify partial methylation of the promoters.
We assessed 92 GCT DNAs representing all histologic subsets of NSGCT, and SGCT, and four normal testes for methylation status of CpG islands of 21 gene promoters by methylation-specific PCR (MSP) (Fig.
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