Example sentences for: cpg

How can you use “cpg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Considering the varying definitions of CpG islands (especially the minimum length of CpG-rich region), this number is in close agreement with the estimate of 45,000 obtained by Antequera and Bird [ 28] using methylation-sensitive restriction enzymes.

  • Promoter methylation has been well recognized as an important epigenetic change in the development of cancer [ 1 ] . Normally, CpG islands in the promoter regions of a number of genes are present in an unmethylated state [ 2 ] . Aberrant methylation of CpG islands in promoters is characteristic of several genes in cancer leading to loss of gene expression.

  • Therefore, promoter-finding methods based on sequence information successfully identify almost the exact same subset of promoters, owing to the high correlation with the subset of promoters located within CpG islands [ 8].

  • The rare CpG hypermethylation seen in five SGCT patients may be due to the existence of a minor NSGCT component that might have escaped the histologic diagnosis.

  • CpG_ISLANDS


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