Example sentences for: cpg

How can you use “cpg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • MeCP2's functional structure consists of an 84 amino acid methyl-binding domain (MBD) [ 11 ] and a 104 amino acid transcriptional repression domain (TRD) [ 12 ] . The MBD is able to bind to 5-methyl cytosine residues of a single CpG dinucleotide [ 11 ] . Under the current model, MeCP2 binds to DNA, then complexes with Sin3A through the TRD and recruits histone deacetylases (HDAC).

  • Alternatively, while MeCP2's expression is ubiquitous, other methyl-CpG binding proteins that exist within complexes, MBD1 and MBD2 [ 19 ] or Kaiso [ 20 ] , may reduce the effect of mutations in MECP2 in peripheral organ systems while the lack of such redundancy may lead to a more pronounced phenotype in the brain.

  • LINE1 elements again differed from other features, showing a negative correlation with exons, CpG islands, GC content and Alu repeats.

  • The MSP method detects only methylation of full-length CpG islands and cannot identify partial methylation of the promoters.

  • We assessed 92 GCT DNAs representing all histologic subsets of NSGCT, and SGCT, and four normal testes for methylation status of CpG islands of 21 gene promoters by methylation-specific PCR (MSP) (Fig.


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