Words similar to cox-
Example sentences for: cox-
How can you use “cox-” in a sentence? Here are some example sentences to help you improve your vocabulary:
The "COX-2 inhibitor" could be a godsend for those suffering from rheumatoid arthritis.
One of the proposed mechanisms for the chemopreventive properties of aspirin and other NSAIDs points to the observation that NSAIDs inhibit prostaglandin (PG)-endoperoxide synthase (cyclooxygenase) enzymes [ 24 ] , of which two forms of similar enzymatic activity exist, COX-1 and COX-2.
The COX-2 probe was random primed following the directions of the manufacturer (Megaprime ®, Amersham/Pharmacia).
We have previously shown that acute endotoxemia primes adherent lung neutrophils for increased production of reactive oxygen and nitrogen intermediates suggesting that these cells are functionally activated [ 9 ] . The work reported here, demonstrates that adherent vascular lung neutrophils from endotoxin treated rats are also activated to respond to chemotactic stimuli and to express TNF-α and COX-2 mRNA and protein.
Previous studies have demonstrated that acute endotoxemia activates peripheral blood neutrophils to release prostaglandins [ 17 ] . These lipid mediators are produced during inflammatory reactions largely via the enzyme COX-2 [ 18 ] . We found that COX-2 mRNA was markedly upregulated (40-400 fold) in adherent vascular lung neutrophils following endotoxin treatment of the animals (Fig.
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