Example sentences for: cox-

How can you use “cox-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The "COX-2 inhibitor" could be a godsend for those suffering from rheumatoid arthritis.

  • One of the proposed mechanisms for the chemopreventive properties of aspirin and other NSAIDs points to the observation that NSAIDs inhibit prostaglandin (PG)-endoperoxide synthase (cyclooxygenase) enzymes [ 24 ] , of which two forms of similar enzymatic activity exist, COX-1 and COX-2.

  • The COX-2 probe was random primed following the directions of the manufacturer (Megaprime ®, Amersham/Pharmacia).

  • We have previously shown that acute endotoxemia primes adherent lung neutrophils for increased production of reactive oxygen and nitrogen intermediates suggesting that these cells are functionally activated [ 9 ] . The work reported here, demonstrates that adherent vascular lung neutrophils from endotoxin treated rats are also activated to respond to chemotactic stimuli and to express TNF-α and COX-2 mRNA and protein.

  • Previous studies have demonstrated that acute endotoxemia activates peripheral blood neutrophils to release prostaglandins [ 17 ] . These lipid mediators are produced during inflammatory reactions largely via the enzyme COX-2 [ 18 ] . We found that COX-2 mRNA was markedly upregulated (40-400 fold) in adherent vascular lung neutrophils following endotoxin treatment of the animals (Fig.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast