Words similar to cox-
Example sentences for: cox-
How can you use “cox-” in a sentence? Here are some example sentences to help you improve your vocabulary:
The pRET2 incorporates long-terminal repeats from the myeloproliferative sarcoma virus [ 7 ] , and a point mutation in the primer binding site [ 8 ] . A vector expressing the human cyclooxygenase-2 (COX-2) cDNA was constructed in the same backbone (pRET2.COX2).
C/EBP is previously reported to be an important accessory factor for transactivation by several other transcription factors [ 26 ] . C/EBPβ was shown to transactivate the α1-acid glycoprotein gene promoter even when mutated in the DNA-binding domain, and this activation appeared to depend on protein-protein interaction with glucocorticoid receptor through the leucine zipper region [ 27 ] . Recently, a conserved domain in C/EBPα and C/EBPβ was shown to mediate cAMP responsiveness, strengthening the fact that C/EBP may be characterized as a cAMP-responsive nuclear regulator [ 28 29 ] . On the COX-2 promoter in granulosa cells, cAMP-mediated regulation was shown to be mediated primarily by an E-box that bind USF1 and USF2 isoforms in a manner resembling the RIIβ E-box in Sertoli cells [ 30 ] . Transactivation of the COX-2 gene in skin carcinoma cells is highly dependent on this E-box together with a C/EBP binding site that bind C/EBPβ and C/EBPδ [ 31 ] . These data strengthens a model of formation of a cAMP-responsive unit (CRU) containing USF and C/EBP.
A recent study did not demonstrate an association between COX-2 expression and pathological or clinical factors, such as age, gender, survival, tumor size, stage and vascular invasion [ 26 ] , confirming results reported in previous studies [ 14 17 22 ] . To our knowledge, only three population studies, with varying methodological rigor, have been published examining the relationship between NSAID use and pancreatic cancer [ 27 28 29 ] . Each of these studies reported a lack of association.
The COX-1 isoform is constitutively expressed in blood vessels, while expression of the COX-2 isoform is induced in new blood vessels.
The drop in performance is directly correlated to phytoestrogen levels in brain and the effects of phytoestrogens on brain CALB and COX-2 levels, in that phytoestrogens were identified as having a negative relationship with CALB (-0.
Loading...