Example sentences for: counter-selectable

How can you use “counter-selectable” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • That observation led to the development of a system for investigating the expansion of trinucleotide repeats in yeast in which the promoter is combined with the URA3 gene, a widely used counter-selectable marker [ 19 23 ] . In our work, we took advantage of the specific spacing requirements of the ADH1 promoter to develop a novel TAR cloning procedure that allows isolation of genomic regions that lack ARS elements.

  • Vectors with a counter-selectable marker at the end of a targeting hook are not efficient for gene isolation from complex genomes

  • The first strategy exploited a vector with a counter-selectable marker placed at the end of one of the targeting hooks.

  • To eliminate background resulting from re-circularization of the vector during TAR cloning, we investigated two different strategies based on use of a counter-selectable marker.

  • These results demonstrate that TAR cloning vectors with a counter-selectable marker at the end of one of the hooks are inefficient for cloning the genes from complex mammalian genomes.


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