Example sentences for: cornelia

How can you use “cornelia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Finally, mutation of a factor required to load cohesin—the protein complex responsible for chromosome cohesion—onto chromosomes appears to cause Cornelia de Lange syndrome, a clinically heterogeneous developmental disorder that may include facial dysmorphia, upper-extremity malformations, hirsutism, cardiac defects, growth and cognitive retardation, and gastrointestinal disorders [3,4,5].

  • This model further speculates that rather than Cornelia de Lange syndrome stemming from a cohesin loading defect, the failure to unload cohesin from regions that need to be transcribed leads to transcriptional defects that cause the syndrome.


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