Words similar to copii
Example sentences for: copii
How can you use “copii” in a sentence? Here are some example sentences to help you improve your vocabulary:
Bet3p is part of a complex that binds to COPII derived vesicles and is required for vesicle targeting [ 47 48 ] . Sec27p is a component of the COPI coat and required for Golgi to ER transport [ 49 50 ] . Like SEC23 and SEC13 mutants, others have reported that mutants in BET3 and SEC27 result in an over-proliferation of ER membranes [ 49 51 ] .
The screen for NPC assembly/mislocalization mutants identified two genes that are part of the COPII coat, SEC13 and SEC23 . To test if other members of the COPII coat complex were isolated in the screen, conditional alleles in SEC16 , SEC24 , SEC31 , SAR1 , and SEC12 were kindly provided by other investigators, and tested directly for their effect on NPC localization.
Interestingly, we found by direct testing that mutant alleles corresponding to the genes for all known COPII coat components resulted in altered GFP-Nup localization.
We conclude there is no absolute correlation between localization of a COPII component at the NPC and its ability to disrupt NPC structure/function.
We feel this conclusion is also supported by our observation that the distribution of GFP-Nups was altered in mutants for all COPII coat components.