Words similar to cop

Example sentences for: cop

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As a first step to locate the signals responsible for the subcellular localization of mammalian COP1, we made a series of deletion constructs of GFP-MmCOP1 (Fig 5A).
Our studies suggest the mammalian COP1 RING finger acts as a structural scaffold by placing the two clusters of positive residues within the right spatial proximity for binding to the nuclear import machinery.
Petunia CHS also lends itself to detect somatic transitions in epialleles due to its indeterminate growth habit, whereas Arabidopsis COP1 is more suitable for monitoring early epigenetic activity in seedlings and rosette plants.
A partial cDNA clone homologous to AtCOP1 has been previously identified in mammals, containing all three conserved protein-protein interaction domains [ 20 ] . Remarkably, when expressed in plant cells, the mammalian COP1-reporter fusion protein exhibited a light-regulated nuclear localization pattern similar to AtCOP1 [ 20 ] . Although mammalian COP1 failed to rescue the Arabidopsis cop1 mutants, over-expression of the amino-terminal half of mammalian COP1 in Arabidopsis caused a dominant-negative phenotype, resembling the effect of over-expressing the corresponding fragment of AtCOP1 [ 20 21 ] .
Furthermore, activation of COP provides the initial driving force for osmotic swelling and bleb formation.