Words similar to complexed
Example sentences for: complexed
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This generates the necessary 3' hydroxyl group for DNA polymerases (pol β, δ or ε, in eukaryotes) to insert the correct nucleotide in later steps in the base excision repair pathway (BER-pathway) [ 7 8 ] . Recent crystal structures of huAPE1 complexed with DNA containing an abasic site [ 9 10 11 ] , combined with sequence analysis and site-directed mutagenesis, have defined the residues that participate in metal ion based cleavage of the phosphate backbone of the DNA [ 12 13 14 15 16 17 ] .
Although β1 integrins were predominantly present in the dense membrane fraction on a sucrose gradient, the subset of β1 integrins complexed with CD98 was localized to the 'light' membrane fractions.
In the former case, the DNA backbone sites located closest to one another are across the minor groove and separated in sequence by 3 bp [ 28 29 30 ] . The second proposal is supported by a recent 2.2 angstrom NarL-DNA structure for NarL-C-terminal domain complexed to a synthetic 7-2-7 NarL consensus binding site where the protein causes a conformational change of B-DNA to A-DNA (Ann Maris, personal communication).
However as a defense mechanism, availability of iron for the bacteria is limited in the host as most of it complexed to ferritin, transferrin, hemoglobin, heme and hemosiderin [ 1 2 3 4 ] . For pathogenic bacteria to be able to establish an infection, it must compete with and obtain iron from the host's iron binding protein [ 5 ] . The bacteria have evolved a number of diverse mechanisms utilize the host iron.
showed that fragments of the Gal4 activation region between 17 and 41 amino acids in length provide activation functions of a magnitude in rough proportion to their length [ 24 ] . This result suggests that short sequences are capable of stimulating transcription when complexed with promotor elements and that their effect is amplified by increasing the total content of such short sequences.
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