Words similar to complexed
Example sentences for: complexed
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Root segments were placed in 10 mm NMR tubes with their axes aligned parallel to the tube axis and perfused with aerated buffer solutions containing 50 mM glucose, 1 mM Ca 2+, 10 mM potassium-gadolinium EDTA, 0.5 mM EDTA, 5 mM methylethylsulfonate (MES) at pH 6 with or without 3% D 2 O. The gadolinium (Gd) was used to separate intracellular from extracellular signals [ 70] and is complexed to prevent toxicity.
Since most current docking programs treat the receptor and/or ligand as rigid objects, this represents an important cause of failure to predict the correct binding enzyme-substrate energies [ 18 ] . We address this problem by performing Molecular Dynamic (MD) simulations on HIV-1 protease-inhibitor complexed and using the resulting structures to calculate the binding energies by AutoDock, a ligand flexible docking program.
This generates the necessary 3' hydroxyl group for DNA polymerases (pol β, δ or ε, in eukaryotes) to insert the correct nucleotide in later steps in the base excision repair pathway (BER-pathway) [ 7 8 ] . Recent crystal structures of huAPE1 complexed with DNA containing an abasic site [ 9 10 11 ] , combined with sequence analysis and site-directed mutagenesis, have defined the residues that participate in metal ion based cleavage of the phosphate backbone of the DNA [ 12 13 14 15 16 17 ] .
Pro-MMP-2 complexed with TIMP-2 binds to a TIMP-2 binding site on the membrane-bound MMP-14 receptor, and through a conformational change the catalytic domain becomes exposed forming the active enzyme complex.
showed that fragments of the Gal4 activation region between 17 and 41 amino acids in length provide activation functions of a magnitude in rough proportion to their length [ 24 ] . This result suggests that short sequences are capable of stimulating transcription when complexed with promotor elements and that their effect is amplified by increasing the total content of such short sequences.
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