Example sentences for: compartmentalization

How can you use “compartmentalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The intracellular concentration of ThDP has been estimated at 30 μM, with only about 7 percent being free cytosolic and the remainder being enzyme-bound with much of this within mitochondria [ 4 5 ] . Previous findings indicate a complex, cell-type dependent regulation of compartmentalization and intracellular pools of thiamine and its phosphorylated derivatives in response to fluctuating extracellular thiamine levels [ 4 5 6 ] . Hence, thiamine transport, including that by mitochondria, is of interest.

  • Koshland (2002) lists seven features of life: (1) program (DNA), (2) improvisation (response to environment), (3) compartmentalization, (4) energy, (5) regeneration, (6) adaptability, and (7) seclusion (chemical control and selectivity).

  • Interestingly, of the three cell types neuroblastoma cells also are the most resistant to changes in mitochondrial ThDP-utilizing enzyme activity upon progressive depletion of the thiamine made available to the cells [ 6 ] . This suggests that cell-dependent variation in ThDP uptake capacity by mitochondria may contribute to the cell-dependent regulation of ThDP compartmentalization.

  • It has been known for the past decade that compartmentalization of PKA can occur through association with A-kinase anchoring proteins (AKAPs).

  • Clearly, differences in mitochondrial transporter affinities do not contribute to the cell-type dependent regulation of ThDP compartmentalization.


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